Murphy PV - Search Results

1

Influence of protein (human galectin-3) design on aspects of lectin activity.

García Caballero G, Beckwith D, Shilova NV, Gabba A, Kutzner TJ, Ludwig AK, Manning JC, Kaltner H, Sinowatz F, Cudic M, Bovin NV, Murphy PV, Gabius HJ. García Caballero G, et al. Among authors: murphy pv. Histochem Cell Biol. 2020 Aug;154(2):135-153. doi: 10.1007/s00418-020-01859-9. Epub 2020 Apr 25. Histochem Cell Biol. 2020. PMID: 32335744 Free PMC article.

2

Phenylenediamine-based bivalent glycocyclophanes: synthesis and analysis of the influence of scaffold rigidity and ligand spacing on lectin binding in cell systems with different glycomic profiles.

André S, Velasco-Torrijos T, Leyden R, Gouin S, Tosin M, Murphy PV, Gabius HJ. André S, et al. Among authors: murphy pv. Org Biomol Chem. 2009 Nov 21;7(22):4715-25. doi: 10.1039/b913010a. Epub 2009 Sep 23. Org Biomol Chem. 2009. PMID: 19865709

3

Synthesis of bivalent lactosides based on terephthalamide, N,N'-diglucosylterephthalamide, and glycophane scaffolds and assessment of their inhibitory capacity on medically relevant lectins.

Leyden R, Velasco-Torrijos T, André S, Gouin S, Gabius HJ, Murphy PV. Leyden R, et al. Among authors: murphy pv. J Org Chem. 2009 Dec 4;74(23):9010-26. doi: 10.1021/jo901667r. J Org Chem. 2009. PMID: 19899775

4

Synthesis of bivalent lactosides and their activity as sensors for differences between lectins in inter- and intrafamily comparisons.

André S, Jarikote DV, Yan D, Vincenz L, Wang GN, Kaltner H, Murphy PV, Gabius HJ. André S, et al. Among authors: murphy pv. Bioorg Med Chem Lett. 2012 Jan 1;22(1):313-8. doi: 10.1016/j.bmcl.2011.11.010. Epub 2011 Nov 10. Bioorg Med Chem Lett. 2012. PMID: 22142540

5

Bi- to tetravalent glycoclusters: synthesis, structure-activity profiles as lectin inhibitors and impact of combining both valency and headgroup tailoring on selectivity.

Wang GN, André S, Gabius HJ, Murphy PV. Wang GN, et al. Among authors: murphy pv. Org Biomol Chem. 2012 Sep 14;10(34):6893-907. doi: 10.1039/c2ob25870f. Epub 2012 Jul 30. Org Biomol Chem. 2012. PMID: 22842468

6

The third dimension of reading the sugar code by lectins: design of glycoclusters with cyclic scaffolds as tools with the aim to define correlations between spatial presentation and activity.

Murphy PV, André S, Gabius HJ. Murphy PV, et al. Molecules. 2013 Apr 4;18(4):4026-53. doi: 10.3390/molecules18044026. Molecules. 2013. PMID: 23558543 Free PMC article. Review.

7

Combining glycocluster synthesis with protein engineering: an approach to probe into the significance of linker length in a tandem-repeat-type lectin (galectin-4).

André S, Wang GN, Gabius HJ, Murphy PV. André S, et al. Among authors: murphy pv. Carbohydr Res. 2014 May 7;389:25-38. doi: 10.1016/j.carres.2013.12.024. Epub 2014 Jan 11. Carbohydr Res. 2014. PMID: 24698724

8

Lectins: getting familiar with translators of the sugar code.

André S, Kaltner H, Manning JC, Murphy PV, Gabius HJ. André S, et al. Among authors: murphy pv. Molecules. 2015 Jan 22;20(2):1788-823. doi: 10.3390/molecules20021788. Molecules. 2015. PMID: 25621423 Free PMC article. Review.

9

Bi- to tetravalent glycoclusters presenting GlcNAc/GalNAc as inhibitors: from plant agglutinins to human macrophage galactose-type lectin (CD301) and galectins.

André S, O'Sullivan S, Koller C, Murphy PV, Gabius HJ. André S, et al. Among authors: murphy pv. Org Biomol Chem. 2015 Apr 14;13(14):4190-203. doi: 10.1039/c5ob00048c. Epub 2015 Feb 27. Org Biomol Chem. 2015. PMID: 25721929

10

Engineering a therapeutic lectin by uncoupling mitogenicity from antiviral activity.

Swanson MD, Boudreaux DM, Salmon L, Chugh J, Winter HC, Meagher JL, André S, Murphy PV, Oscarson S, Roy R, King S, Kaplan MH, Goldstein IJ, Tarbet EB, Hurst BL, Smee DF, de la Fuente C, Hoffmann HH, Xue Y, Rice CM, Schols D, Garcia JV, Stuckey JA, Gabius HJ, Al-Hashimi HM, Markovitz DM. Swanson MD, et al. Among authors: murphy pv. Cell. 2015 Oct 22;163(3):746-58. doi: 10.1016/j.cell.2015.09.056. Epub 2015 Oct 22. Cell. 2015. PMID: 26496612 Free PMC article.

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