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Bioreactor-based mass production of human iPSC-derived macrophages enables immunotherapies against bacterial airway infections.
Ackermann M, Kempf H, Hetzel M, Hesse C, Hashtchin AR, Brinkert K, Schott JW, Haake K, Kühnel MP, Glage S, Figueiredo C, Jonigk D, Sewald K, Schambach A, Wronski S, Moritz T, Martin U, Zweigerdt R, Munder A, Lachmann N. Ackermann M, et al. Among authors: kempf h. Nat Commun. 2018 Nov 30;9(1):5088. doi: 10.1038/s41467-018-07570-7. Nat Commun. 2018. PMID: 30504915 Free PMC article.
iPSC-Derived Macrophages Effectively Treat Pulmonary Alveolar Proteinosis in Csf2rb-Deficient Mice.
Mucci A, Lopez-Rodriguez E, Hetzel M, Liu S, Suzuki T, Happle C, Ackermann M, Kempf H, Hillje R, Kunkiel J, Janosz E, Brennig S, Glage S, Bankstahl JP, Dettmer S, Rodt T, Gohring G, Trapnell B, Hansen G, Trapnell C, Knudsen L, Lachmann N, Moritz T. Mucci A, et al. Among authors: kempf h. Stem Cell Reports. 2018 Sep 11;11(3):696-710. doi: 10.1016/j.stemcr.2018.07.006. Epub 2018 Aug 9. Stem Cell Reports. 2018. PMID: 30100408 Free PMC article.
Stiff matrix induces switch to pure β-cardiac myosin heavy chain expression in human ESC-derived cardiomyocytes.
Weber N, Schwanke K, Greten S, Wendland M, Iorga B, Fischer M, Geers-Knörr C, Hegermann J, Wrede C, Fiedler J, Kempf H, Franke A, Piep B, Pfanne A, Thum T, Martin U, Brenner B, Zweigerdt R, Kraft T. Weber N, et al. Among authors: kempf h. Basic Res Cardiol. 2016 Nov;111(6):68. doi: 10.1007/s00395-016-0587-9. Epub 2016 Oct 14. Basic Res Cardiol. 2016. PMID: 27743117
Fast and efficient multitransgenic modification of human pluripotent stem cells.
Schwanke K, Merkert S, Kempf H, Hartung S, Jara-Avaca M, Templin C, Göhring G, Haverich A, Martin U, Zweigerdt R. Schwanke K, et al. Among authors: kempf h. Hum Gene Ther Methods. 2014 Apr;25(2):136-53. doi: 10.1089/hgtb.2012.248. Epub 2014 Mar 21. Hum Gene Ther Methods. 2014. PMID: 24483184 Free PMC article.
Continuous WNT Control Enables Advanced hPSC Cardiac Processing and Prognostic Surface Marker Identification in Chemically Defined Suspension Culture.
Halloin C, Schwanke K, Löbel W, Franke A, Szepes M, Biswanath S, Wunderlich S, Merkert S, Weber N, Osten F, de la Roche J, Polten F, Christoph Wollert K, Kraft T, Fischer M, Martin U, Gruh I, Kempf H, Zweigerdt R. Halloin C, et al. Among authors: kempf h. Stem Cell Reports. 2019 Aug 13;13(2):366-379. doi: 10.1016/j.stemcr.2019.06.004. Epub 2019 Jul 25. Stem Cell Reports. 2019. PMID: 31353227 Free PMC article.
Differentiation of Human Pluripotent Stem Cells into Functional Endothelial Cells in Scalable Suspension Culture.
Olmer R, Engels L, Usman A, Menke S, Malik MNH, Pessler F, Göhring G, Bornhorst D, Bolten S, Abdelilah-Seyfried S, Scheper T, Kempf H, Zweigerdt R, Martin U. Olmer R, et al. Among authors: kempf h. Stem Cell Reports. 2018 May 8;10(5):1657-1672. doi: 10.1016/j.stemcr.2018.03.017. Epub 2018 Apr 19. Stem Cell Reports. 2018. PMID: 29681541 Free PMC article.
Airway basal cells show a dedifferentiated KRT17highPhenotype and promote fibrosis in idiopathic pulmonary fibrosis.
Jaeger B, Schupp JC, Plappert L, Terwolbeck O, Artysh N, Kayser G, Engelhard P, Adams TS, Zweigerdt R, Kempf H, Lienenklaus S, Garrels W, Nazarenko I, Jonigk D, Wygrecka M, Klatt D, Schambach A, Kaminski N, Prasse A. Jaeger B, et al. Among authors: kempf h. Nat Commun. 2022 Sep 26;13(1):5637. doi: 10.1038/s41467-022-33193-0. Nat Commun. 2022. PMID: 36163190 Free PMC article.
170 results