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213 results

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Notch Signaling Mediates Differentiation in Barrett's Esophagus and Promotes Progression to Adenocarcinoma.
Kunze B, Wein F, Fang HY, Anand A, Baumeister T, Strangmann J, Gerland S, Ingermann J, Münch NS, Wiethaler M, Sahm V, Hidalgo-Sastre A, Lange S, Lightdale CJ, Bokhari A, Falk GW, Friedman RA, Ginsberg GG, Iyer PG, Jin Z, Nakagawa H, Shawber CJ, Nguyen T, Raab WJ, Dalerba P, Rustgi AK, Sepulveda AR, Wang KK, Schmid RM, Wang TC, Abrams JA, Quante M. Kunze B, et al. Among authors: sepulveda ar. Gastroenterology. 2020 Aug;159(2):575-590. doi: 10.1053/j.gastro.2020.04.033. Epub 2020 Apr 20. Gastroenterology. 2020. PMID: 32325086 Free PMC article.
Randomized Controlled Trial of the Gastrin/CCK2 Receptor Antagonist Netazepide in Patients with Barrett's Esophagus.
Abrams JA, Del Portillo A, Hills C, Compres G, Friedman RA, Cheng B, Poneros J, Lightdale CJ, De La Rue R, di Pietro M, Fitzgerald RC, Sepulveda A, Wang TC. Abrams JA, et al. Cancer Prev Res (Phila). 2021 Jun;14(6):675-682. doi: 10.1158/1940-6207.CAPR-21-0050. Epub 2021 Mar 29. Cancer Prev Res (Phila). 2021. PMID: 33782049 Free PMC article. Clinical Trial.
Gastrin stimulates a cholecystokinin-2-receptor-expressing cardia progenitor cell and promotes progression of Barrett's-like esophagus.
Lee Y, Urbanska AM, Hayakawa Y, Wang H, Au AS, Luna AM, Chang W, Jin G, Bhagat G, Abrams JA, Friedman RA, Varro A, Wang KK, Boyce M, Rustgi AK, Sepulveda AR, Quante M, Wang TC. Lee Y, et al. Among authors: sepulveda ar. Oncotarget. 2017 Jan 3;8(1):203-214. doi: 10.18632/oncotarget.10667. Oncotarget. 2017. PMID: 27448962 Free PMC article.
CXCR4 Is a Potential Target for Diagnostic PET/CT Imaging in Barrett's Dysplasia and Esophageal Adenocarcinoma.
Fang HY, Münch NS, Schottelius M, Ingermann J, Liu H, Schauer M, Stangl S, Multhoff G, Steiger K, Gerngroß C, Jesinghaus M, Weichert W, Kühl AA, Sepulveda AR, Wester HJ, Wang TC, Quante M. Fang HY, et al. Among authors: sepulveda ar. Clin Cancer Res. 2018 Mar 1;24(5):1048-1061. doi: 10.1158/1078-0432.CCR-17-1756. Epub 2017 Dec 5. Clin Cancer Res. 2018. PMID: 29208671
High-resolution genomic alterations in Barrett's metaplasia of patients who progress to esophageal dysplasia and adenocarcinoma.
Sepulveda JL, Komissarova EV, Kongkarnka S, Friedman RA, Davison JM, Levy B, Bryk D, Jobanputra V, Del Portillo A, Falk GW, Sonett JR, Lightdale CJ, Abrams JA, Wang TC, Sepulveda AR. Sepulveda JL, et al. Among authors: sepulveda ar. Int J Cancer. 2019 Nov 15;145(10):2754-2766. doi: 10.1002/ijc.32351. Epub 2019 May 2. Int J Cancer. 2019. PMID: 31001805 Free PMC article.
LIN28B promotes colon cancer progression and metastasis.
King CE, Cuatrecasas M, Castells A, Sepulveda AR, Lee JS, Rustgi AK. King CE, et al. Among authors: sepulveda ar. Cancer Res. 2011 Jun 15;71(12):4260-8. doi: 10.1158/0008-5472.CAN-10-4637. Epub 2011 Apr 21. Cancer Res. 2011. PMID: 21512136 Free PMC article.
Evaluation of Mutational Testing of Preneoplastic Barrett's Mucosa by Next-Generation Sequencing of Formalin-Fixed, Paraffin-Embedded Endoscopic Samples for Detection of Concurrent Dysplasia and Adenocarcinoma in Barrett's Esophagus.
Del Portillo A, Lagana SM, Yao Y, Uehara T, Jhala N, Ganguly T, Nagy P, Gutierrez J, Luna A, Abrams J, Liu Y, Brand R, Sepulveda JL, Falk GW, Sepulveda AR. Del Portillo A, et al. Among authors: sepulveda jl, sepulveda ar. J Mol Diagn. 2015 Jul;17(4):412-9. doi: 10.1016/j.jmoldx.2015.02.006. Epub 2015 Jun 8. J Mol Diagn. 2015. PMID: 26068095 Free PMC article.
Transitional basal cells at the squamous-columnar junction generate Barrett's oesophagus.
Jiang M, Li H, Zhang Y, Yang Y, Lu R, Liu K, Lin S, Lan X, Wang H, Wu H, Zhu J, Zhou Z, Xu J, Lee DK, Zhang L, Lee YC, Yuan J, Abrams JA, Wang TC, Sepulveda AR, Wu Q, Chen H, Sun X, She J, Chen X, Que J. Jiang M, et al. Among authors: sepulveda ar. Nature. 2017 Oct 26;550(7677):529-533. doi: 10.1038/nature24269. Epub 2017 Oct 12. Nature. 2017. PMID: 29019984 Free PMC article.
213 results