Kim S - Search Results

1

Synthesis and Structure-Activity Relationships of Arylsulfonamides as AIMP2-DX2 Inhibitors for the Development of a Novel Anticancer Therapy.

Sivaraman A, Kim DG, Bhattarai D, Kim M, Lee HY, Lim S, Kong J, Goo JI, Shim S, Lee S, Suh YG, Choi Y, Kim S, Lee K. Sivaraman A, et al. Among authors: kim dg, kim s, kim m. J Med Chem. 2020 May 28;63(10):5139-5158. doi: 10.1021/acs.jmedchem.9b01961. Epub 2020 Apr 21. J Med Chem. 2020. PMID: 32315177

2

ERK-dependent phosphorylation of the linker and substrate-binding domain of HSP70 increases folding activity and cell proliferation.

Lim S, Kim DG, Kim S. Lim S, et al. Among authors: kim dg, kim s. Exp Mol Med. 2019 Sep 26;51(9):1-14. doi: 10.1038/s12276-019-0317-0. Exp Mol Med. 2019. PMID: 31558706 Free PMC article.

3

Targeting the interaction of AIMP2-DX2 with HSP70 suppresses cancer development.

Lim S, Cho HY, Kim DG, Roh Y, Son SY, Mushtaq AU, Kim M, Bhattarai D, Sivaraman A, Lee Y, Lee J, Yang WS, Kim HK, Kim MH, Lee K, Jeon YH, Kim S. Lim S, et al. Among authors: kim dg, kim hk, kim s, kim m, kim mh. Nat Chem Biol. 2020 Jan;16(1):31-41. doi: 10.1038/s41589-019-0415-2. Epub 2019 Dec 2. Nat Chem Biol. 2020. PMID: 31792442

4

2-Aminophenylpyrimidines as Novel Inhibitors of Aminoacyl-tRNA Synthetase Interacting Multifunctional Protein 2 (AIMP2)-DX2 for Lung Cancer Treatment.

Lee S, Kim DG, Kim K, Kim T, Lim S, Kong H, Kim S, Suh YG. Lee S, et al. Among authors: kim dg, kim t, kim s, kim k. J Med Chem. 2020 Apr 23;63(8):3908-3914. doi: 10.1021/acs.jmedchem.9b01765. Epub 2020 Apr 1. J Med Chem. 2020. PMID: 32208684

5

Cell-based analysis of pairwise interactions between the components of the multi-tRNA synthetase complex.

Kong J, Kim S. Kong J, et al. Among authors: kim s. FASEB J. 2020 Aug;34(8):10476-10488. doi: 10.1096/fj.202000418R. Epub 2020 Jun 15. FASEB J. 2020. PMID: 32539228

6

Identification of Thieno[3,2-d]pyrimidine Derivatives as Dual Inhibitors of Focal Adhesion Kinase and FMS-like Tyrosine Kinase 3.

Cho H, Shin I, Yoon H, Jeon E, Lee J, Kim Y, Ryu S, Song C, Kwon NH, Moon Y, Kim S, Kim ND, Choi HG, Sim T. Cho H, et al. Among authors: kim s, kim nd, kim y. J Med Chem. 2021 Aug 26;64(16):11934-11957. doi: 10.1021/acs.jmedchem.1c00459. Epub 2021 Jul 29. J Med Chem. 2021. PMID: 34324343

7

AIMP2-DX2 provides therapeutic interface to control KRAS-driven tumorigenesis.

Kim DG, Choi Y, Lee Y, Lim S, Kong J, Song J, Roh Y, Harmalkar DS, Lee K, Goo JI, Cho HY, Mushtaq AU, Lee J, Park SH, Kim D, Min BS, Lee KY, Jeon YH, Lee S, Lee K, Kim S. Kim DG, et al. Among authors: kim d, kim s. Nat Commun. 2022 May 11;13(1):2572. doi: 10.1038/s41467-022-30149-2. Nat Commun. 2022. PMID: 35546148 Free PMC article.

8

Synthesis and discovery of the first potent proteolysis targeting chimaera (PROTAC) degrader of AIMP2-DX2 as a lung cancer drug.

Lee B, Kim DG, Lee A, Kim YM, Cui L, Kim S, Choi I. Lee B, et al. Among authors: kim dg, kim ym, kim s. J Enzyme Inhib Med Chem. 2023 Dec;38(1):51-66. doi: 10.1080/14756366.2022.2135510. J Enzyme Inhib Med Chem. 2023. PMID: 36305287 Free PMC article.

9

Branched oligomerization of cell-permeable peptides markedly enhances the transduction efficiency of adenovirus into mesenchymal stem cells.

Park SH, Doh J, Park SI, Lim JY, Kim SM, Youn JI, Jin HT, Seo SH, Song MY, Sung SY, Kim M, Hwang SJ, Choi JM, Lee SK, Lee HY, Lim CL, Chung YJ, Yang D, Kim HN, Lee ZH, Choi KY, Jeun SS, Sung YC. Park SH, et al. Among authors: kim hn, kim m, kim sm. Gene Ther. 2010 Aug;17(8):1052-61. doi: 10.1038/gt.2010.58. Epub 2010 May 20. Gene Ther. 2010. PMID: 20485381

10

EPRS1 Controls the TGF-β Signaling Pathway via Interaction with TβRI in Hepatic Stellate Cell.

Yoon I, Song JA, Suh JH, Kim S, Son J, Kim JH, Jang SY, Hwang KY, Kim MH, Kim S. Yoon I, et al. Among authors: kim s, kim mh, kim jh. Mol Cell Biol. 2023;43(5):223-240. doi: 10.1080/10985549.2023.2205344. Epub 2023 May 8. Mol Cell Biol. 2023. PMID: 37154023 Free PMC article.

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