Longley DB - Search Results

1

The SCF^Skp2 ubiquitin ligase complex modulates TRAIL-R2-induced apoptosis by regulating FLIP(L).

Roberts JZ, Holohan C, Sessler T, Fox J, Crawford N, Riley JS, Khawaja H, Majkut J, Evergren E, Humphreys LM, Ferris J, Higgins C, Espona-Fiedler M, Moynagh P, McDade SS, Longley DB. Roberts JZ, et al. Among authors: longley db. Cell Death Differ. 2020 Sep;27(9):2726-2741. doi: 10.1038/s41418-020-0539-7. Epub 2020 Apr 20. Cell Death Differ. 2020. PMID: 32313199 Free PMC article.

2

c-FLIP inhibits chemotherapy-induced colorectal cancer cell death.

Longley DB, Wilson TR, McEwan M, Allen WL, McDermott U, Galligan L, Johnston PG. Longley DB, et al. Oncogene. 2006 Feb 9;25(6):838-48. doi: 10.1038/sj.onc.1209122. Oncogene. 2006. PMID: 16247474

3

Chemotherapy and TRAIL-mediated colon cancer cell death: the roles of p53, TRAIL receptors, and c-FLIP.

Galligan L, Longley DB, McEwan M, Wilson TR, McLaughlin K, Johnston PG. Galligan L, et al. Among authors: longley db. Mol Cancer Ther. 2005 Dec;4(12):2026-36. doi: 10.1158/1535-7163.MCT-05-0262. Mol Cancer Ther. 2005. PMID: 16373718

4

Cellular FLICE-inhibitory protein regulates chemotherapy-induced apoptosis in breast cancer cells.

Rogers KM, Thomas M, Galligan L, Wilson TR, Allen WL, Sakai H, Johnston PG, Longley DB. Rogers KM, et al. Among authors: longley db. Mol Cancer Ther. 2007 May;6(5):1544-51. doi: 10.1158/1535-7163.MCT-06-0673. Mol Cancer Ther. 2007. PMID: 17513603

5

c-FLIP: a key regulator of colorectal cancer cell death.

Wilson TR, McLaughlin KM, McEwan M, Sakai H, Rogers KM, Redmond KM, Johnston PG, Longley DB. Wilson TR, et al. Among authors: longley db. Cancer Res. 2007 Jun 15;67(12):5754-62. doi: 10.1158/0008-5472.CAN-06-3585. Cancer Res. 2007. PMID: 17575142 Free article.

6

Interleukin-8 signaling attenuates TRAIL- and chemotherapy-induced apoptosis through transcriptional regulation of c-FLIP in prostate cancer cells.

Wilson C, Wilson T, Johnston PG, Longley DB, Waugh DJ. Wilson C, et al. Among authors: longley db. Mol Cancer Ther. 2008 Sep;7(9):2649-61. doi: 10.1158/1535-7163.MCT-08-0148. Mol Cancer Ther. 2008. PMID: 18790747

7

Combined inhibition of FLIP and XIAP induces Bax-independent apoptosis in type II colorectal cancer cells.

Wilson TR, McEwan M, McLaughlin K, Le Clorennec C, Allen WL, Fennell DA, Johnston PG, Longley DB. Wilson TR, et al. Among authors: longley db. Oncogene. 2009 Jan 8;28(1):63-72. doi: 10.1038/onc.2008.366. Epub 2008 Sep 29. Oncogene. 2009. PMID: 18820704

8

Procaspase 8 overexpression in non-small-cell lung cancer promotes apoptosis induced by FLIP silencing.

Wilson TR, Redmond KM, McLaughlin KM, Crawford N, Gately K, O'Byrne K, Le-Clorrenec C, Holohan C, Fennell DA, Johnston PG, Longley DB. Wilson TR, et al. Among authors: longley db. Cell Death Differ. 2009 Oct;16(10):1352-61. doi: 10.1038/cdd.2009.76. Epub 2009 Jun 19. Cell Death Differ. 2009. PMID: 19543235

9

Prognostic significance of TRAIL signaling molecules in stage II and III colorectal cancer.

McLornan DP, Barrett HL, Cummins R, McDermott U, McDowell C, Conlon SJ, Coyle VM, Van Schaeybroeck S, Wilson R, Kay EW, Longley DB, Johnston PG. McLornan DP, et al. Among authors: longley db. Clin Cancer Res. 2010 Jul 1;16(13):3442-51. doi: 10.1158/1078-0432.CCR-10-0052. Epub 2010 Jun 22. Clin Cancer Res. 2010. PMID: 20570920 Free PMC article.

10

Voltage dependent anion channel-1 regulates death receptor mediated apoptosis by enabling cleavage of caspase-8.

Chacko AD, Liberante F, Paul I, Longley DB, Fennell DA. Chacko AD, et al. Among authors: longley db. BMC Cancer. 2010 Jul 20;10:380. doi: 10.1186/1471-2407-10-380. BMC Cancer. 2010. PMID: 20646307 Free PMC article.

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