Middleton G - Search Results

1

Use of an Integrated Pan-Cancer Oncology Enrichment Next-Generation Sequencing Assay to Measure Tumour Mutational Burden and Detect Clinically Actionable Variants.

Pestinger V, Smith M, Sillo T, Findlay JM, Laes JF, Martin G, Middleton G, Taniere P, Beggs AD. Pestinger V, et al. Among authors: middleton g. Mol Diagn Ther. 2020 Jun;24(3):339-349. doi: 10.1007/s40291-020-00462-x. Mol Diagn Ther. 2020. PMID: 32306292 Free PMC article.

2

An immunogenomic stratification of colorectal cancer: Implications for development of targeted immunotherapy.

Lal N, Beggs AD, Willcox BE, Middleton GW. Lal N, et al. Oncoimmunology. 2015 Apr 2;4(3):e976052. doi: 10.4161/2162402X.2014.976052. eCollection 2015 Mar. Oncoimmunology. 2015. PMID: 25949894 Free PMC article.

3

Methylation changes in the TFAP2E promoter region are associated with BRAF mutation and poorer overall & disease free survival in colorectal cancer.

Beggs AD, Dilworth MP, Domingo E, Midgley R, Kerr D, Tomlinson IP, Middleton GW. Beggs AD, et al. Oncoscience. 2015 Mar 23;2(5):508-16. doi: 10.18632/oncoscience.149. eCollection 2015. Oncoscience. 2015. PMID: 26097884 Free PMC article.

4

Endothelial protein C receptor is overexpressed in colorectal cancer as a result of amplification and hypomethylation of chromosome 20q.

Lal N, Willcox CR, Beggs A, Taniere P, Shikotra A, Bradding P, Adams R, Fisher D, Middleton G, Tselepis C, Willcox BE. Lal N, et al. Among authors: middleton g. J Pathol Clin Res. 2017 Jul 14;3(3):155-170. doi: 10.1002/cjp2.70. eCollection 2017 Jul. J Pathol Clin Res. 2017. PMID: 28770100 Free PMC article.

5

KRAS Mutation and Consensus Molecular Subtypes 2 and 3 Are Independently Associated with Reduced Immune Infiltration and Reactivity in Colorectal Cancer.

Lal N, White BS, Goussous G, Pickles O, Mason MJ, Beggs AD, Taniere P, Willcox BE, Guinney J, Middleton GW. Lal N, et al. Among authors: middleton gw. Clin Cancer Res. 2018 Jan 1;24(1):224-233. doi: 10.1158/1078-0432.CCR-17-1090. Epub 2017 Oct 23. Clin Cancer Res. 2018. PMID: 29061646 Free PMC article.

6

Epidermal Growth Factor Receptor (EGFR) Kinase Inhibitors and Non-Small Cell Lung Cancer (NSCLC) - Advances in Molecular Diagnostic Techniques to Facilitate Targeted Therapy.

Ghafoor Q, Baijal S, Taniere P, O'Sullivan B, Evans M, Middleton G. Ghafoor Q, et al. Among authors: middleton g. Pathol Oncol Res. 2018 Oct;24(4):723-731. doi: 10.1007/s12253-017-0377-1. Epub 2017 Dec 21. Pathol Oncol Res. 2018. PMID: 29270776 Free article. Review.

7

Development and Validation of a Combined Hypoxia and Immune Prognostic Classifier for Head and Neck Cancer.

Brooks JM, Menezes AN, Ibrahim M, Archer L, Lal N, Bagnall CJ, von Zeidler SV, Valentine HR, Spruce RJ, Batis N, Bryant JL, Hartley M, Kaul B, Ryan GB, Bao R, Khattri A, Lee SP, Ogbureke KUE, Middleton G, Tennant DA, Beggs AD, Deeks J, West CML, Cazier JB, Willcox BE, Seiwert TY, Mehanna H. Brooks JM, et al. Among authors: middleton g. Clin Cancer Res. 2019 Sep 1;25(17):5315-5328. doi: 10.1158/1078-0432.CCR-18-3314. Epub 2019 Jun 10. Clin Cancer Res. 2019. PMID: 31182433

8

Mechanisms of immunogenicity in colorectal cancer.

Sillo TO, Beggs AD, Morton DG, Middleton G. Sillo TO, et al. Among authors: middleton g. Br J Surg. 2019 Sep;106(10):1283-1297. doi: 10.1002/bjs.11204. Epub 2019 Jun 19. Br J Surg. 2019. PMID: 31216061 Free PMC article. Review.

9

Correction to: Use of an Integrated Pan-Cancer Oncology Enrichment Next-Generation Sequencing Assay to Measure Tumour Mutational Burden and Detect Clinically Actionable Variants.

Pestinger V, Smith M, Sillo T, Findlay JM, Laes JF, Martin G, Middleton G, Taniere P, Beggs AD. Pestinger V, et al. Among authors: middleton g. Mol Diagn Ther. 2020 Aug;24(4):505. doi: 10.1007/s40291-020-00479-2. Mol Diagn Ther. 2020. PMID: 32572786 Free PMC article.

10

Paradox breaker BRAF inhibitors have comparable potency and MAPK pathway reactivation to encorafenib in BRAF mutant colorectal cancer.

Pickles OJ, Drozd A, Tee L, Beggs AD, Middleton GW. Pickles OJ, et al. Oncotarget. 2020 Aug 25;11(34):3188-3197. doi: 10.18632/oncotarget.27681. eCollection 2020 Aug 25. Oncotarget. 2020. PMID: 32922659 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

340 results

Search Page