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Glioblastoma hijacks microglial gene expression to support tumor growth.
Maas SLN, Abels ER, Van De Haar LL, Zhang X, Morsett L, Sil S, Guedes J, Sen P, Prabhakar S, Hickman SE, Lai CP, Ting DT, Breakefield XO, Broekman MLD, El Khoury J. Maas SLN, et al. Among authors: lai cp. J Neuroinflammation. 2020 Apr 16;17(1):120. doi: 10.1186/s12974-020-01797-2. J Neuroinflammation. 2020. PMID: 32299465 Free PMC article.
Directly visualized glioblastoma-derived extracellular vesicles transfer RNA to microglia/macrophages in the brain.
van der Vos KE, Abels ER, Zhang X, Lai C, Carrizosa E, Oakley D, Prabhakar S, Mardini O, Crommentuijn MH, Skog J, Krichevsky AM, Stemmer-Rachamimov A, Mempel TR, El Khoury J, Hickman SE, Breakefield XO. van der Vos KE, et al. Neuro Oncol. 2016 Jan;18(1):58-69. doi: 10.1093/neuonc/nov244. Epub 2015 Oct 3. Neuro Oncol. 2016. PMID: 26433199 Free PMC article.
SCS macrophages suppress melanoma by restricting tumor-derived vesicle-B cell interactions.
Pucci F, Garris C, Lai CP, Newton A, Pfirschke C, Engblom C, Alvarez D, Sprachman M, Evavold C, Magnuson A, von Andrian UH, Glatz K, Breakefield XO, Mempel TR, Weissleder R, Pittet MJ. Pucci F, et al. Among authors: lai cp. Science. 2016 Apr 8;352(6282):242-6. doi: 10.1126/science.aaf1328. Epub 2016 Mar 17. Science. 2016. PMID: 26989197 Free PMC article.
86 results