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A Subcutaneous Implant of Tenofovir Alafenamide Fumarate Causes Local Inflammation and Tissue Necrosis in Rabbits and Macaques.
Su JT, Simpson SM, Sung S, Tfaily EB, Veazey R, Marzinke M, Qiu J, Watrous D, Widanapathirana L, Pearson E, Peet MM, Karunakaran D, Grasperge B, Dobek G, Cain CM, Hope T, Kiser PF. Su JT, et al. Among authors: karunakaran d. Antimicrob Agents Chemother. 2020 Feb 21;64(3):e01893-19. doi: 10.1128/AAC.01893-19. Print 2020 Feb 21. Antimicrob Agents Chemother. 2020. PMID: 31871073 Free PMC article.
Design and Testing of a Cabotegravir Implant for HIV Prevention.
Karunakaran D, Simpson SM, Su JT, Bryndza-Tfaily E, Hope TJ, Veazey R, Dobek G, Qiu J, Watrous D, Sung S, Chacon JE, Kiser PF. Karunakaran D, et al. J Control Release. 2021 Feb 10;330:658-668. doi: 10.1016/j.jconrel.2020.12.024. Epub 2020 Dec 19. J Control Release. 2021. PMID: 33347943 Free PMC article.
Long-acting intramuscular injections of ELQ-331, an antimalarial agent.
Karunakaran D, Mutyam SK, Fu M, Chen J, Pham KHN, Pou S, Winter RW, Nilsen A, Dodean RA, Smilkstein MJ, Riscoe MK, Shankar G. Karunakaran D, et al. Eur J Pharm Sci. 2024 May 8;198:106795. doi: 10.1016/j.ejps.2024.106795. Online ahead of print. Eur J Pharm Sci. 2024. PMID: 38729224 Free article.
Risk factors associated with safety of preschool peanut oral immunotherapy.
Karunakaran D, Chan ES, Zhang Q, Bone JN, Carr S, Kapur S, Rex GA, McHenry M, Cameron SB, Cook VE, Leo S, Wong T, Gerstner TV, Yeung J, Abrams EM, Mak R, Erdle SC, Soller L. Karunakaran D, et al. J Allergy Clin Immunol Glob. 2023 Mar 21;2(2):100094. doi: 10.1016/j.jacig.2023.100094. eCollection 2023 May. J Allergy Clin Immunol Glob. 2023. PMID: 37780798 Free PMC article.
HDAC7 is an immunometabolic switch triaging danger signals for engagement of antimicrobial versus inflammatory responses in macrophages.
Das Gupta K, Ramnath D, von Pein JB, Curson JEB, Wang Y, Abrol R, Kakkanat A, Moradi SV, Gunther KS, Murthy AMV, Stocks CJ, Kapetanovic R, Reid RC, Iyer A, Ilka ZC, Nauseef WM, Plan M, Luo L, Stow JL, Schroder K, Karunakaran D, Alexandrov K, Shakespear MR, Schembri MA, Fairlie DP, Sweet MJ. Das Gupta K, et al. Among authors: karunakaran d. Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2212813120. doi: 10.1073/pnas.2212813120. Epub 2023 Jan 17. Proc Natl Acad Sci U S A. 2023. PMID: 36649417 Free PMC article.
Epigenetic Silencing of RIPK3 in Hepatocytes Prevents MLKL-mediated Necroptosis From Contributing to Liver Pathologies.
Preston SP, Stutz MD, Allison CC, Nachbur U, Gouil Q, Tran BM, Duvivier V, Arandjelovic P, Cooney JP, Mackiewicz L, Meng Y, Schaefer J, Bader SM, Peng H, Valaydon Z, Rajasekaran P, Jennison C, Lopaticki S, Farrell A, Ryan M, Howell J, Croagh C, Karunakaran D, Schuster-Klein C, Murphy JM, Fifis T, Christophi C, Vincan E, Blewitt ME, Thompson A, Boddey JA, Doerflinger M, Pellegrini M. Preston SP, et al. Among authors: karunakaran d. Gastroenterology. 2022 Dec;163(6):1643-1657.e14. doi: 10.1053/j.gastro.2022.08.040. Epub 2022 Aug 28. Gastroenterology. 2022. PMID: 36037995 Free article.
62 results