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Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation.
Jiao H, Wachsmuth L, Kumari S, Schwarzer R, Lin J, Eren RO, Fisher A, Lane R, Young GR, Kassiotis G, Kaiser WJ, Pasparakis M. Jiao H, et al. Among authors: lane r. Nature. 2020 Apr;580(7803):391-395. doi: 10.1038/s41586-020-2129-8. Epub 2020 Mar 25. Nature. 2020. PMID: 32296175 Free PMC article.
ZBP1/DAI Drives RIPK3-Mediated Cell Death Induced by IFNs in the Absence of RIPK1.
Ingram JP, Thapa RJ, Fisher A, Tummers B, Zhang T, Yin C, Rodriguez DA, Guo H, Lane R, Williams R, Slifker MJ, Basagoudanavar SH, Rall GF, Dillon CP, Green DR, Kaiser WJ, Balachandran S. Ingram JP, et al. Among authors: lane r. J Immunol. 2019 Sep 1;203(5):1348-1355. doi: 10.4049/jimmunol.1900216. Epub 2019 Jul 29. J Immunol. 2019. PMID: 31358656 Free PMC article.
Mitochondrial metabolites extend lifespan.
Mishur RJ, Khan M, Munkácsy E, Sharma L, Bokov A, Beam H, Radetskaya O, Borror M, Lane R, Bai Y, Rea SL. Mishur RJ, et al. Among authors: lane r. Aging Cell. 2016 Apr;15(2):336-48. doi: 10.1111/acel.12439. Epub 2016 Jan 5. Aging Cell. 2016. PMID: 26729005 Free PMC article.
The role of mitochondrial dysfunction in age-related diseases.
Lane RK, Hilsabeck T, Rea SL. Lane RK, et al. Biochim Biophys Acta. 2015 Nov;1847(11):1387-400. doi: 10.1016/j.bbabio.2015.05.021. Epub 2015 Jun 4. Biochim Biophys Acta. 2015. PMID: 26050974 Free PMC article. Review.
1,950 results