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Discovery of [1,2,4]Triazolo[1,5-a]pyridine Derivatives as Potent and Orally Bioavailable RORγt Inverse Agonists.
Nakajima R, Oono H, Sugiyama S, Matsueda Y, Ida T, Kakuda S, Hirata J, Baba A, Makino A, Matsuyama R, White RD, Wurz RΡ, Shin Y, Min X, Guzman-Perez A, Wang Z, Symons A, Singh SK, Mothe SR, Belyakov S, Chakrabarti A, Shuto S. Nakajima R, et al. Among authors: singh sk. ACS Med Chem Lett. 2020 Feb 27;11(4):528-534. doi: 10.1021/acsmedchemlett.9b00649. eCollection 2020 Apr 9. ACS Med Chem Lett. 2020. PMID: 32292560 Free PMC article.
Heterocyclic core analogs of a direct thrombin inhibitor.
Blizzard TA, Singh S, Patil B, Chidurala N, Komanduri V, Debnath S, Belyakov S, Crespo A, Struck A, Kurtz M, Wiltsie J, Shen X, Sonatore L, Arocho M, Lewis D, Ogletree M, Biftu T. Blizzard TA, et al. Bioorg Med Chem Lett. 2014 Feb 15;24(4):1111-5. doi: 10.1016/j.bmcl.2014.01.002. Epub 2014 Jan 10. Bioorg Med Chem Lett. 2014. PMID: 24461292
Discovery of MK-8718, an HIV Protease Inhibitor Containing a Novel Morpholine Aspartate Binding Group.
Bungard CJ, Williams PD, Ballard JE, Bennett DJ, Beaulieu C, Bahnck-Teets C, Carroll SS, Chang RK, Dubost DC, Fay JF, Diamond TL, Greshock TJ, Hao L, Holloway MK, Felock PJ, Gesell JJ, Su HP, Manikowski JJ, McKay DJ, Miller M, Min X, Molinaro C, Moradei OM, Nantermet PG, Nadeau C, Sanchez RI, Satyanarayana T, Shipe WD, Singh SK, Truong VL, Vijayasaradhi S, Wiscount CM, Vacca JP, Crane SN, McCauley JA. Bungard CJ, et al. Among authors: singh sk. ACS Med Chem Lett. 2016 May 9;7(7):702-7. doi: 10.1021/acsmedchemlett.6b00135. eCollection 2016 Jul 14. ACS Med Chem Lett. 2016. PMID: 27437081 Free PMC article.
Enhancing the oral bioavailability of fisetin: polysaccharide-based self nano-emulsifying spheroids for colon-targeted delivery.
Gunjal P, Vishwas S, Kumar R, Bashir B, Kumar B, Khurana N, Gulati M, Gupta G, Prasher P, Kumbhar P, Disouza J, Kuppusamy G, Mohammed Y, Dureja H, Dua K, Singh SK. Gunjal P, et al. Among authors: singh sk. Drug Deliv Transl Res. 2024 May 24. doi: 10.1007/s13346-024-01634-6. Online ahead of print. Drug Deliv Transl Res. 2024. PMID: 38789909
4,505 results