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Adipose triglyceride lipase plays a key role in the supply of the working muscle with fatty acids.
Schoiswohl G, Schweiger M, Schreiber R, Gorkiewicz G, Preiss-Landl K, Taschler U, Zierler KA, Radner FP, Eichmann TO, Kienesberger PC, Eder S, Lass A, Haemmerle G, Alsted TJ, Kiens B, Hoefler G, Zechner R, Zimmermann R. Schoiswohl G, et al. J Lipid Res. 2010 Mar;51(3):490-9. doi: 10.1194/jlr.M001073. Epub 2009 Nov 25. J Lipid Res. 2010. PMID: 19965578 Free PMC article.
Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance.
Taschler U, Radner FP, Heier C, Schreiber R, Schweiger M, Schoiswohl G, Preiss-Landl K, Jaeger D, Reiter B, Koefeler HC, Wojciechowski J, Theussl C, Penninger JM, Lass A, Haemmerle G, Zechner R, Zimmermann R. Taschler U, et al. Among authors: schoiswohl g. J Biol Chem. 2011 May 20;286(20):17467-77. doi: 10.1074/jbc.M110.215434. Epub 2011 Mar 23. J Biol Chem. 2011. PMID: 21454566 Free PMC article.
ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1.
Haemmerle G, Moustafa T, Woelkart G, Büttner S, Schmidt A, van de Weijer T, Hesselink M, Jaeger D, Kienesberger PC, Zierler K, Schreiber R, Eichmann T, Kolb D, Kotzbeck P, Schweiger M, Kumari M, Eder S, Schoiswohl G, Wongsiriroj N, Pollak NM, Radner FP, Preiss-Landl K, Kolbe T, Rülicke T, Pieske B, Trauner M, Lass A, Zimmermann R, Hoefler G, Cinti S, Kershaw EE, Schrauwen P, Madeo F, Mayer B, Zechner R. Haemmerle G, et al. Among authors: schoiswohl g. Nat Med. 2011 Aug 21;17(9):1076-85. doi: 10.1038/nm.2439. Nat Med. 2011. PMID: 21857651 Free PMC article.
Skeletal muscle triacylglycerol hydrolysis does not influence metabolic complications of obesity.
Sitnick MT, Basantani MK, Cai L, Schoiswohl G, Yazbeck CF, Distefano G, Ritov V, DeLany JP, Schreiber R, Stolz DB, Gardner NP, Kienesberger PC, Pulinilkunnil T, Zechner R, Goodpaster BH, Coen P, Kershaw EE. Sitnick MT, et al. Among authors: schoiswohl g. Diabetes. 2013 Oct;62(10):3350-61. doi: 10.2337/db13-0500. Epub 2013 Jul 8. Diabetes. 2013. PMID: 23835334 Free PMC article.
Fasting-induced G0/G1 switch gene 2 and FGF21 expression in the liver are under regulation of adipose tissue derived fatty acids.
Jaeger D, Schoiswohl G, Hofer P, Schreiber R, Schweiger M, Eichmann TO, Pollak NM, Poecher N, Grabner GF, Zierler KA, Eder S, Kolb D, Radner FP, Preiss-Landl K, Lass A, Zechner R, Kershaw EE, Haemmerle G. Jaeger D, et al. Among authors: schoiswohl g. J Hepatol. 2015 Aug;63(2):437-45. doi: 10.1016/j.jhep.2015.02.035. Epub 2015 Feb 27. J Hepatol. 2015. PMID: 25733154 Free PMC article.
Loss of ABHD15 Impairs the Anti-lipolytic Action of Insulin by Altering PDE3B Stability and Contributes to Insulin Resistance.
Xia W, Pessentheiner AR, Hofer DC, Amor M, Schreiber R, Schoiswohl G, Eichmann TO, Walenta E, Itariu B, Prager G, Hackl H, Stulnig T, Kratky D, Rülicke T, Bogner-Strauss JG. Xia W, et al. Among authors: schoiswohl g. Cell Rep. 2018 May 15;23(7):1948-1961. doi: 10.1016/j.celrep.2018.04.055. Cell Rep. 2018. PMID: 29768196 Free PMC article.
Intestine-Specific Overexpression of Carboxylesterase 2c Protects Mice From Diet-Induced Liver Steatosis and Obesity.
Maresch LK, Benedikt P, Feiler U, Eder S, Zierler KA, Taschler U, Kolleritsch S, Eichmann TO, Schoiswohl G, Leopold C, Wieser BI, Lackner C, Rülicke T, van Klinken J, Kratky D, Moustafa T, Hoefler G, Haemmerle G. Maresch LK, et al. Among authors: schoiswohl g. Hepatol Commun. 2018 Dec 17;3(2):227-245. doi: 10.1002/hep4.1292. eCollection 2019 Feb. Hepatol Commun. 2018. PMID: 30766961 Free PMC article.
Hepatocyte-specific deletion of lysosomal acid lipase leads to cholesteryl ester but not triglyceride or retinyl ester accumulation.
Pajed L, Wagner C, Taschler U, Schreiber R, Kolleritsch S, Fawzy N, Pototschnig I, Schoiswohl G, Pusch LM, Wieser BI, Vesely P, Hoefler G, Eichmann TO, Zimmermann R, Lass A. Pajed L, et al. Among authors: schoiswohl g. J Biol Chem. 2019 Jun 7;294(23):9118-9133. doi: 10.1074/jbc.RA118.007201. Epub 2019 Apr 25. J Biol Chem. 2019. PMID: 31023823 Free PMC article.
43 results