Nielsen F - Search Results

1

P-Glycoprotein Inhibition Exacerbates Paclitaxel Neurotoxicity in Neurons and Patients With Cancer.

Stage TB, Mortensen C, Khalaf S, Steffensen V, Hammer HS, Xiong C, Nielsen F, Poetz O, Svenningsen ÅF, Rodriguez-Antona C, Kroetz DL. Stage TB, et al. Among authors: nielsen f. Clin Pharmacol Ther. 2020 Sep;108(3):671-680. doi: 10.1002/cpt.1847. Epub 2020 May 23. Clin Pharmacol Ther. 2020. PMID: 32275773 Free PMC article.

2

A gene-gene interaction between polymorphisms in the OCT2 and MATE1 genes influences the renal clearance of metformin.

Christensen MM, Pedersen RS, Stage TB, Brasch-Andersen C, Nielsen F, Damkier P, Beck-Nielsen H, Brøsen K. Christensen MM, et al. Among authors: nielsen f. Pharmacogenet Genomics. 2013 Oct;23(10):526-34. doi: 10.1097/FPC.0b013e328364a57d. Pharmacogenet Genomics. 2013. PMID: 23873119 Clinical Trial.

3

CYP2C19*17 increases clopidogrel-mediated platelet inhibition but does not alter the pharmacokinetics of the active metabolite of clopidogrel.

Pedersen RS, Nielsen F, Stage TB, Vinholt PJ, el Achwah AB, Damkier P, Brosen K. Pedersen RS, et al. Among authors: nielsen f. Clin Exp Pharmacol Physiol. 2014 Nov;41(11):870-8. doi: 10.1111/1440-1681.12297. Clin Exp Pharmacol Physiol. 2014. PMID: 25115434 Clinical Trial.

4

Microdialysis as a tool to determine the local tissue concentration of dicloxacillin in man.

Hansen KK, Nielsen F, Stage TB, Jørgensen U, Skov O, Rasmussen LE. Hansen KK, et al. Among authors: nielsen f. Br J Clin Pharmacol. 2018 Mar;84(3):533-541. doi: 10.1111/bcp.13468. Epub 2017 Dec 7. Br J Clin Pharmacol. 2018. PMID: 29105799 Free PMC article. Clinical Trial.

5

Dicloxacillin induces CYP2C19, CYP2C9 and CYP3A4 in vivo and in vitro.

Stage TB, Graff M, Wong S, Rasmussen LL, Nielsen F, Pottegård A, Brøsen K, Kroetz DL, Khojasteh SC, Damkier P. Stage TB, et al. Among authors: nielsen f. Br J Clin Pharmacol. 2018 Mar;84(3):510-519. doi: 10.1111/bcp.13467. Epub 2018 Jan 10. Br J Clin Pharmacol. 2018. PMID: 29105855 Free PMC article. Clinical Trial.

6

Pharmacokinetics of metformin in patients with gastrointestinal intolerance.

McCreight LJ, Stage TB, Connelly P, Lonergan M, Nielsen F, Prehn C, Adamski J, Brøsen K, Pearson ER. McCreight LJ, et al. Among authors: nielsen f. Diabetes Obes Metab. 2018 Jul;20(7):1593-1601. doi: 10.1111/dom.13264. Epub 2018 Mar 23. Diabetes Obes Metab. 2018. PMID: 29457876 Free PMC article. Clinical Trial.

7

Flucloxacillin Is a Weak Inducer of CYP3A4 in Healthy Adults and 3D Spheroid of Primary Human Hepatocytes.

Iversen DB, Dunvald AD, Jespersen DM, Nielsen F, Brøsen K, Damkier P, Hammer HS, Pötz O, Järvinen E, Stage TB. Iversen DB, et al. Among authors: nielsen f. Clin Pharmacol Ther. 2023 Aug;114(2):434-445. doi: 10.1002/cpt.2959. Epub 2023 Jun 8. Clin Pharmacol Ther. 2023. PMID: 37235733 Clinical Trial.

8

Impact of quinidine on plasma and cerebrospinal fluid concentrations of codeine and morphine after codeine intake.

Sindrup SH, Hofmann U, Asmussen J, Mikus G, Brøsen K, Nielsen F, Ingwersen SH, Broen Christensen C. Sindrup SH, et al. Among authors: nielsen f. Eur J Clin Pharmacol. 1996;49(6):503-9. doi: 10.1007/BF00195938. Eur J Clin Pharmacol. 1996. PMID: 8706777 Clinical Trial.

9

Impact of CYP2C8*3 on paclitaxel clearance: a population pharmacokinetic and pharmacogenomic study in 93 patients with ovarian cancer.

Bergmann TK, Brasch-Andersen C, Gréen H, Mirza M, Pedersen RS, Nielsen F, Skougaard K, Wihl J, Keldsen N, Damkier P, Friberg LE, Peterson C, Vach W, Karlsson MO, Brosen K. Bergmann TK, et al. Among authors: nielsen f. Pharmacogenomics J. 2011 Apr;11(2):113-20. doi: 10.1038/tpj.2010.19. Epub 2010 Apr 6. Pharmacogenomics J. 2011. PMID: 20368717

10

Neurotoxicity and low paclitaxel clearance associated with concomitant clopidogrel therapy in a 60-year-old Caucasian woman with ovarian carcinoma.

Bergmann TK, Filppula AM, Launiainen T, Nielsen F, Backman J, Brosen K. Bergmann TK, et al. Among authors: nielsen f. Br J Clin Pharmacol. 2016 Feb;81(2):313-5. doi: 10.1111/bcp.12795. Br J Clin Pharmacol. 2016. PMID: 26446447 Free PMC article.

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