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The protein family TcTASV-C is a novel Trypanosoma cruzi virulence factor secreted in extracellular vesicles by trypomastigotes and highly expressed in bloodstream forms.
Caeiro LD, Alba-Soto CD, Rizzi M, Solana ME, Rodriguez G, Chidichimo AM, Rodriguez ME, Sánchez DO, Levy GV, Tekiel V. Caeiro LD, et al. Among authors: sanchez do. PLoS Negl Trop Dis. 2018 May 4;12(5):e0006475. doi: 10.1371/journal.pntd.0006475. eCollection 2018 May. PLoS Negl Trop Dis. 2018. PMID: 29727453 Free PMC article.
TcTASV Antigens of Trypanosoma cruzi: Utility for Diagnosis and High Accuracy as Biomarkers of Treatment Efficacy in Pediatric Patients.
Floridia-Yapur N, Monje-Rumi M, Ragone P, Lauthier JJ, Tomasini N, Alberti D'Amato A, Diosque P, Cimino R, Gil JF, Sanchez DO, Nasser JR, Tekiel V. Floridia-Yapur N, et al. Among authors: sanchez do. Am J Trop Med Hyg. 2019 Nov;101(5):1135-1138. doi: 10.4269/ajtmh.18-0936. Am J Trop Med Hyg. 2019. PMID: 31516110 Free PMC article.
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