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Ruthenium(II)/Benzonitrile Complex Induces Cytotoxic Effect in Sarcoma-180 Cells by Caspase-Mediated and Tp53/p21-Mediated Apoptosis, with Moderate Brine Shrimp Toxicity.
Faria RS, Silva HD, Mello-Andrade F, Pires WC, de Castro Pereira F, de Lima AP, de Fátima Oliveira Santos S, Teixeira TM, da Silva PFF, Naves PLF, Batista AA, da Silva Oliveira RJ, Reis RM, de Paula Silveira-Lacerda E. Faria RS, et al. Among authors: mello andrade f. Biol Trace Elem Res. 2020 Dec;198(2):669-680. doi: 10.1007/s12011-020-02098-8. Epub 2020 Apr 8. Biol Trace Elem Res. 2020. PMID: 32266641
Ru(II)/diphenylphosphine/pyridine-6-thiolate complexes induce S-180 cell apoptosis through intrinsic mitochondrial pathway involving inhibition of Bcl-2 and p53/Bax activation.
Pires WC, Lima BAV, de Castro Pereira F, Lima AP, Mello-Andrade F, Silva HD, da Silva MM, Colina-Vegas L, Ellena J, Batista AA, de Paul Silveira-Lacerda E. Pires WC, et al. Mol Cell Biochem. 2018 Jan;438(1-2):199-217. doi: 10.1007/s11010-017-3129-3. Epub 2017 Aug 9. Mol Cell Biochem. 2018. PMID: 28795366
cis-[RuCl(BzCN)(bipy)(dppe)]PF6 induces anti-angiogenesis and apoptosis by a mechanism of caspase-dependent involving DNA damage, PARP activation, and Tp53 induction in Ehrlich tumor cells.
Magalhães LF, Mello-Andrade F, Pires WC, Silva HD, da Silva PFF, Macedo LM, Henrique de Castro C, Carneiro CC, Cardoso CG, de Melo Reis PR, Camargo de Oliveira L, Caetano RR, Batista AA, Silveira-Lacerda EP. Magalhães LF, et al. Chem Biol Interact. 2017 Dec 25;278:101-113. doi: 10.1016/j.cbi.2017.09.013. Epub 2017 Sep 19. Chem Biol Interact. 2017. PMID: 28935426
Antitumor effectiveness and mechanism of action of Ru(II)/amino acid/diphosphine complexes in the peritoneal carcinomatosis progression.
Mello-Andrade F, da Costa WL, Pires WC, Pereira FC, Cardoso CG, Lino-Junior RS, Irusta VRC, Carneiro CC, de Melo-Reis PR, Castro CH, Almeida MAP, Batista AA, Silveira-Lacerda EP. Mello-Andrade F, et al. Tumour Biol. 2017 Oct;39(10):1010428317695933. doi: 10.1177/1010428317695933. Tumour Biol. 2017. PMID: 29019283 Free article.
Ru(II)-Based Amino Acid Complexes Show Promise for Leukemia Treatment: Cytotoxicity and Some Light on their Mechanism of Action.
de Lima AP, Almeida MAP, Mello-Andrade F, de Castro Pereira F, Pires WC, Abreu DC, de Souza Velozo-Sá V, Batista AA, de Paula Silveira-Lacerda E. de Lima AP, et al. Among authors: mello andrade f. Biol Trace Elem Res. 2020 Sep;197(1):123-131. doi: 10.1007/s12011-019-01976-0. Epub 2019 Nov 26. Biol Trace Elem Res. 2020. PMID: 31773484
Heterobimetallic Ru(ii)/Fe(ii) complexes as potent anticancer agents against breast cancer cells, inducing apoptosis through multiple targets.
Guedes APM , Mello-Andrade F , Pires WC , de Sousa MAM , da Silva PFF , de Camargo MS , Gemeiner H , Amauri MA , Gomes Cardoso C , de Melo Reis PR , Silveira-Lacerda EP , Batista AA . Guedes APM , et al. Among authors: mello andrade f. Metallomics. 2020 Apr 1;12(4):547-561. doi: 10.1039/c9mt00272c. Epub 2020 Feb 28. Metallomics. 2020. PMID: 32108850
Influence of genetic polymorphisms in glutathione-S-transferases gene in response to imatinib among Brazilian patients with chronic myeloid leukemia.
Delmond KA, Delleon H, Goveia RM, Teixeira TM, Abreu DC, Mello-Andrade F, Reis AADS, Silva DME, Barbosa ADP, Tavares RS, Anunciação CE, Silveira-Lacerda E. Delmond KA, et al. Among authors: mello andrade f. Mol Biol Rep. 2021 Mar;48(3):2035-2046. doi: 10.1007/s11033-020-06093-z. Epub 2021 Mar 11. Mol Biol Rep. 2021. PMID: 33709282
Ruthenium (II)/allopurinol complex inhibits breast cancer progression via multiple targets.
Travassos IO, Mello-Andrade F, Caldeira RP, Pires WC, da Silva PFF, Correa RS, Teixeira T, Martins-Oliveira A, Batista AA, de Silveira-Lacerda EP. Travassos IO, et al. Among authors: mello andrade f. J Biol Inorg Chem. 2021 Jun;26(4):385-401. doi: 10.1007/s00775-021-01862-y. Epub 2021 Apr 10. J Biol Inorg Chem. 2021. PMID: 33837856
15 results