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Interference with ERK-dimerization at the nucleocytosolic interface targets pathological ERK1/2 signaling without cardiotoxic side-effects.
Tomasovic A, Brand T, Schanbacher C, Kramer S, Hümmert MW, Godoy P, Schmidt-Heck W, Nordbeck P, Ludwig J, Homann S, Wiegering A, Shaykhutdinov T, Kratz C, Knüchel R, Müller-Hermelink HK, Rosenwald A, Frey N, Eichler J, Dobrev D, El-Armouche A, Hengstler JG, Müller OJ, Hinrichs K, Cuello F, Zernecke A, Lorenz K. Tomasovic A, et al. Among authors: knuchel r. Nat Commun. 2020 Apr 7;11(1):1733. doi: 10.1038/s41467-020-15505-4. Nat Commun. 2020. PMID: 32265441 Free PMC article.
Biological responses to PDGF-AA versus PDGF-CC in renal fibroblasts.
Seikrit C, Henkel C, van Roeyen CR, Bokemeyer D, Eitner F, Martin IV, Boor P, Knüchel R, Meyer HE, Müller-Newen G, Eriksson U, Floege J, Ostendorf T. Seikrit C, et al. Among authors: knuchel r. Nephrol Dial Transplant. 2013 Apr;28(4):889-900. doi: 10.1093/ndt/gfs509. Epub 2012 Dec 9. Nephrol Dial Transplant. 2013. PMID: 23229927
First report from the German COVID-19 autopsy registry.
von Stillfried S, Bülow RD, Röhrig R, Boor P; German Registry of COVID-19 Autopsies (DeRegCOVID), DeRegCOVID Collaborators. von Stillfried S, et al. Lancet Reg Health Eur. 2022 Feb 18;15:100330. doi: 10.1016/j.lanepe.2022.100330. eCollection 2022 Apr. Lancet Reg Health Eur. 2022. PMID: 35531493 Free PMC article.
Multicentric Analytical and Inter-observer Comparability of Four Clinically Developed Programmed Death-ligand 1 Immunohistochemistry Assays in Advanced Clear-cell Renal Cell Carcinoma.
Sommer U, Eckstein M, Ammann J, Braunschweig T, Macher-Göppinger S, Schwamborn K, Hieke-Schulz S, Harlow G, Flores M, Wullich B, Wirth M, Roth W, Knüchel R, Weichert W, Baretton G, Hartmann A. Sommer U, et al. Among authors: knuchel r. Clin Genitourin Cancer. 2020 Oct;18(5):e629-e642. doi: 10.1016/j.clgc.2020.02.009. Epub 2020 Feb 15. Clin Genitourin Cancer. 2020. PMID: 32178978 Free article.
213 results