One-Step, Rapid, 18F-19F Isotopic Exchange Radiolabeling of Difluoro-dioxaborinins: Substituent Effect on Stability and In Vivo Applications.
An F, Nurili F, Sayman H, Ozer Z, Cakiroglu H, Aras O, Ting R.
An F, et al.
J Med Chem. 2020 Nov 12;63(21):12693-12706. doi: 10.1021/acs.jmedchem.0c00997. Epub 2020 Oct 21.
J Med Chem. 2020.
PMID: 32787084
Free PMC article.
We describe a general method for radiolabeling beta-diketone-bearing molecules with fluoride-18. Radiolabeling was carried out via (18)F-(19)F isotopic exchange on nonradioactive difluoro-dioxaborinins, which were generated by minimally modifying the beta-diketone a …
We describe a general method for radiolabeling beta-diketone-bearing molecules with fluoride-18. Radiolabeling was carried out via (18)F …