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Base editing of the HBG promoter induces potent fetal hemoglobin expression with no detectable off-target mutations in human HSCs.
Han W, Qiu HY, Sun S, Fu ZC, Wang GQ, Qian X, Wang L, Zhai X, Wei J, Wang Y, Guo YL, Cao GH, Ji RJ, Zhang YZ, Ma H, Wang H, Zhao M, Wu J, Bi L, Chen QB, Li Z, Yu L, Mou X, Yin H, Yang L, Chen J, Yang B, Zhang Y. Han W, et al. Among authors: zhang yz, zhang y. Cell Stem Cell. 2023 Dec 7;30(12):1624-1639.e8. doi: 10.1016/j.stem.2023.10.007. Epub 2023 Nov 20. Cell Stem Cell. 2023. PMID: 37989316
Multi-year clinical outcomes of cancers diagnosed following detection by a blood-based multi-cancer early detection (MCED) test.
Buchanan AH, Lennon AM, Choudhry OA, Elias PZ, Rego SP, Sadler JR, Roberta J, Zhang Y, Flake DD, Salvati ZM, Wagner ES, Fishman EK, Papadopoulos N, Beer TM. Buchanan AH, et al. Among authors: zhang y. Cancer Prev Res (Phila). 2024 May 31. doi: 10.1158/1940-6207.CAPR-24-0107. Online ahead of print. Cancer Prev Res (Phila). 2024. PMID: 38819783
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