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Targeting Endoplasmic Reticulum α-Glucosidase I with a Single-Dose Iminosugar Treatment Protects against Lethal Influenza and Dengue Virus Infections.
Warfield KL, Alonzi DS, Hill JC, Caputo AT, Roversi P, Kiappes JL, Sheets N, Duchars M, Dwek RA, Biggins J, Barnard D, Shresta S, Treston AM, Zitzmann N. Warfield KL, et al. Among authors: roversi p. J Med Chem. 2020 Apr 23;63(8):4205-4214. doi: 10.1021/acs.jmedchem.0c00067. Epub 2020 Apr 15. J Med Chem. 2020. PMID: 32227946
3D-Informed Targeting of the Trop-2 Signal-Activation Site Drives Selective Cancer Vulnerability.
Guerra E, Trerotola M, Relli V, Lattanzio R, Tripaldi R, Ceci M, Boujnah K, Pantalone L, Sacchetti A, Havas KM, Simeone P, Travali N, Querzoli P, Pedriali M, Roversi P, Iezzi M, Tinari N, Antolini L, Alberti S. Guerra E, et al. Among authors: roversi p. Mol Cancer Ther. 2023 Jun 1;22(6):790-804. doi: 10.1158/1535-7163.MCT-22-0352. Mol Cancer Ther. 2023. PMID: 36921314
Early management of COPD: where are we now and where do we go from here? A Delphi consensus project.
Di Marco F, Balbo P, de Blasio F, Cardaci V, Crimi N, Girbino G, Pelaia G, Pirina P, Roversi P, Santus P, Scichilone N, Vatrella A, Pasqualetti P, Carone M. Di Marco F, et al. Among authors: roversi p. Int J Chron Obstruct Pulmon Dis. 2019 Feb 4;14:353-360. doi: 10.2147/COPD.S176662. eCollection 2019. Int J Chron Obstruct Pulmon Dis. 2019. PMID: 30787604 Free PMC article. Review.
Complement regulation at the molecular level: the structure of decay-accelerating factor.
Lukacik P, Roversi P, White J, Esser D, Smith GP, Billington J, Williams PA, Rudd PM, Wormald MR, Harvey DJ, Crispin MD, Radcliffe CM, Dwek RA, Evans DJ, Morgan BP, Smith RA, Lea SM. Lukacik P, et al. Among authors: roversi p. Proc Natl Acad Sci U S A. 2004 Feb 3;101(5):1279-84. doi: 10.1073/pnas.0307200101. Epub 2004 Jan 20. Proc Natl Acad Sci U S A. 2004. PMID: 14734808 Free PMC article.
Interdomain conformational flexibility underpins the activity of UGGT, the eukaryotic glycoprotein secretion checkpoint.
Roversi P, Marti L, Caputo AT, Alonzi DS, Hill JC, Dent KC, Kumar A, Levasseur MD, Lia A, Waksman T, Basu S, Soto Albrecht Y, Qian K, McIvor JP, Lipp CB, Siliqi D, Vasiljević S, Mohammed S, Lukacik P, Walsh MA, Santino A, Zitzmann N. Roversi P, et al. Proc Natl Acad Sci U S A. 2017 Aug 8;114(32):8544-8549. doi: 10.1073/pnas.1703682114. Epub 2017 Jul 24. Proc Natl Acad Sci U S A. 2017. PMID: 28739903 Free PMC article.
Target highlights from the first post-PSI CASP experiment (CASP12, May-August 2016).
Kryshtafovych A, Albrecht R, Baslé A, Bule P, Caputo AT, Carvalho AL, Chao KL, Diskin R, Fidelis K, Fontes CMGA, Fredslund F, Gilbert HJ, Goulding CW, Hartmann MD, Hayes CS, Herzberg O, Hill JC, Joachimiak A, Kohring GW, Koning RI, Lo Leggio L, Mangiagalli M, Michalska K, Moult J, Najmudin S, Nardini M, Nardone V, Ndeh D, Nguyen TH, Pintacuda G, Postel S, van Raaij MJ, Roversi P, Shimon A, Singh AK, Sundberg EJ, Tars K, Zitzmann N, Schwede T. Kryshtafovych A, et al. Among authors: roversi p. Proteins. 2018 Mar;86 Suppl 1(Suppl 1):27-50. doi: 10.1002/prot.25392. Epub 2017 Oct 16. Proteins. 2018. PMID: 28960539 Free PMC article.
165 results