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Vaccine Development Against Middle East Respiratory Syndrome.
Lee HY, Nyon MP, Strych U. Lee HY, et al. Among authors: nyon mp. Curr Trop Med Rep. 2016;3(3):80-86. doi: 10.1007/s40475-016-0084-0. Epub 2016 Jul 11. Curr Trop Med Rep. 2016. PMID: 32226714 Free PMC article. Review.
Vitamin D (1,25(OH)2D3) induces α-1-antitrypsin synthesis by CD4+ T cells, which is required for 1,25(OH)2D3-driven IL-10.
Dimeloe S, Rice LV, Chen H, Cheadle C, Raynes J, Pfeffer P, Lavender P, Richards DF, Nyon MP, McDonnell JM, Kemper C, Gooptu B, Hawrylowicz CM. Dimeloe S, et al. Among authors: nyon mp. J Steroid Biochem Mol Biol. 2019 May;189:1-9. doi: 10.1016/j.jsbmb.2019.01.014. Epub 2019 Jan 25. J Steroid Biochem Mol Biol. 2019. PMID: 30690074 Free PMC article.
An integrative approach combining ion mobility mass spectrometry, X-ray crystallography, and nuclear magnetic resonance spectroscopy to study the conformational dynamics of α1 -antitrypsin upon ligand binding.
Nyon MP, Prentice T, Day J, Kirkpatrick J, Sivalingam GN, Levy G, Haq I, Irving JA, Lomas DA, Christodoulou J, Gooptu B, Thalassinos K. Nyon MP, et al. Protein Sci. 2015 Aug;24(8):1301-12. doi: 10.1002/pro.2706. Epub 2015 Jul 14. Protein Sci. 2015. PMID: 26011795 Free PMC article.
Therapeutic target-site variability in α1-antitrypsin characterized at high resolution.
Patschull AO, Segu L, Nyon MP, Lomas DA, Nobeli I, Barrett TE, Gooptu B. Patschull AO, et al. Among authors: nyon mp. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Dec 1;67(Pt 12):1492-7. doi: 10.1107/S1744309111040267. Epub 2011 Nov 25. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011. PMID: 22139150 Free PMC article.
13 results