Furness SGB - Search Results

1

The Molecular Control of Calcitonin Receptor Signaling.

Dal Maso E, Glukhova A, Zhu Y, Garcia-Nafria J, Tate CG, Atanasio S, Reynolds CA, Ramírez-Aportela E, Carazo JM, Hick CA, Furness SGB, Hay DL, Liang YL, Miller LJ, Christopoulos A, Wang MW, Wootten D, Sexton PM. Dal Maso E, et al. Among authors: furness sgb. ACS Pharmacol Transl Sci. 2019 Jan 11;2(1):31-51. doi: 10.1021/acsptsci.8b00056. eCollection 2019 Feb 8. ACS Pharmacol Transl Sci. 2019. PMID: 32219215 Free PMC article.

2

Sites and mechanisms of action of colokinetics at dopamine, ghrelin and serotonin receptors in the rodent lumbosacral defecation centre.

Ringuet MT, Koo A, Furness SGB, McDougall SJ, Furness JB. Ringuet MT, et al. Among authors: furness sgb. J Physiol. 2023 Dec;601(23):5195-5211. doi: 10.1113/JP285217. Epub 2023 Sep 29. J Physiol. 2023. PMID: 37772438 Free PMC article.

3

Receptor activity-modifying proteins differentially modulate the G protein-coupling efficiency of amylin receptors.

Morfis M, Tilakaratne N, Furness SG, Christopoulos G, Werry TD, Christopoulos A, Sexton PM. Morfis M, et al. Endocrinology. 2008 Nov;149(11):5423-31. doi: 10.1210/en.2007-1735. Epub 2008 Jul 3. Endocrinology. 2008. PMID: 18599553

4

Consequences of splice variation on Secretin family G protein-coupled receptor function.

Furness SG, Wootten D, Christopoulos A, Sexton PM. Furness SG, et al. Br J Pharmacol. 2012 May;166(1):98-109. doi: 10.1111/j.1476-5381.2011.01571.x. Br J Pharmacol. 2012. PMID: 21718310 Free PMC article. Review.

5

Small molecule allosteric modulation of the glucagon-like Peptide-1 receptor enhances the insulinotropic effect of oxyntomodulin.

Willard FS, Wootten D, Showalter AD, Savage EE, Ficorilli J, Farb TB, Bokvist K, Alsina-Fernandez J, Furness SG, Christopoulos A, Sexton PM, Sloop KW. Willard FS, et al. Mol Pharmacol. 2012 Dec;82(6):1066-73. doi: 10.1124/mol.112.080432. Epub 2012 Aug 28. Mol Pharmacol. 2012. PMID: 22930710

6

Glucagon-like peptide-1 receptor dimerization differentially regulates agonist signaling but does not affect small molecule allostery.

Harikumar KG, Wootten D, Pinon DI, Koole C, Ball AM, Furness SG, Graham B, Dong M, Christopoulos A, Miller LJ, Sexton PM. Harikumar KG, et al. Proc Natl Acad Sci U S A. 2012 Nov 6;109(45):18607-12. doi: 10.1073/pnas.1205227109. Epub 2012 Oct 22. Proc Natl Acad Sci U S A. 2012. PMID: 23091034 Free PMC article.

7

Recent advances in understanding GLP-1R (glucagon-like peptide-1 receptor) function.

Koole C, Pabreja K, Savage EE, Wootten D, Furness SG, Miller LJ, Christopoulos A, Sexton PM. Koole C, et al. Biochem Soc Trans. 2013 Feb 1;41(1):172-9. doi: 10.1042/BST20120236. Biochem Soc Trans. 2013. PMID: 23356279 Review.

8

Molecular mechanisms underlying physiological and receptor pleiotropic effects mediated by GLP-1R activation.

Pabreja K, Mohd MA, Koole C, Wootten D, Furness SG. Pabreja K, et al. Br J Pharmacol. 2014 Mar;171(5):1114-28. doi: 10.1111/bph.12313. Br J Pharmacol. 2014. PMID: 23889512 Free PMC article. Review.

9

Prolonged calcitonin receptor signaling by salmon, but not human calcitonin, reveals ligand bias.

Andreassen KV, Hjuler ST, Furness SG, Sexton PM, Christopoulos A, Nosjean O, Karsdal MA, Henriksen K. Andreassen KV, et al. PLoS One. 2014 Mar 18;9(3):e92042. doi: 10.1371/journal.pone.0092042. eCollection 2014. PLoS One. 2014. PMID: 24643196 Free PMC article.

10

Biased allosteric modulation at the CaS receptor engendered by structurally diverse calcimimetics.

Cook AE, Mistry SN, Gregory KJ, Furness SG, Sexton PM, Scammells PJ, Conigrave AD, Christopoulos A, Leach K. Cook AE, et al. Br J Pharmacol. 2015 Jan;172(1):185-200. doi: 10.1111/bph.12937. Epub 2014 Dec 1. Br J Pharmacol. 2015. PMID: 25220431 Free PMC article.

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