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CDK1 dependent phosphorylation of hTERT contributes to cancer progression.
Yasukawa M, Ando Y, Yamashita T, Matsuda Y, Shoji S, Morioka MS, Kawaji H, Shiozawa K, Machitani M, Abe T, Yamada S, Kaneko MK, Kato Y, Furuta Y, Kondo T, Shirouzu M, Hayashizaki Y, Kaneko S, Masutomi K. Yasukawa M, et al. Among authors: shirouzu m. Nat Commun. 2020 Mar 25;11(1):1557. doi: 10.1038/s41467-020-15289-7. Nat Commun. 2020. PMID: 32214089 Free PMC article.
Crystal structure of the RUN domain of the RAP2-interacting protein x.
Kukimoto-Niino M, Takagi T, Akasaka R, Murayama K, Uchikubo-Kamo T, Terada T, Inoue M, Watanabe S, Tanaka A, Hayashizaki Y, Kigawa T, Shirouzu M, Yokoyama S. Kukimoto-Niino M, et al. Among authors: shirouzu m. J Biol Chem. 2006 Oct 20;281(42):31843-53. doi: 10.1074/jbc.M604960200. Epub 2006 Aug 23. J Biol Chem. 2006. PMID: 16928684 Free article.
TNIK inhibition abrogates colorectal cancer stemness.
Masuda M, Uno Y, Ohbayashi N, Ohata H, Mimata A, Kukimoto-Niino M, Moriyama H, Kashimoto S, Inoue T, Goto N, Okamoto K, Shirouzu M, Sawa M, Yamada T. Masuda M, et al. Among authors: shirouzu m. Nat Commun. 2016 Aug 26;7:12586. doi: 10.1038/ncomms12586. Nat Commun. 2016. PMID: 27562646 Free PMC article.
Parallel homodimer structures of the extracellular domains of the voltage-gated sodium channel β4 subunit explain its role in cell-cell adhesion.
Shimizu H, Tosaki A, Ohsawa N, Ishizuka-Katsura Y, Shoji S, Miyazaki H, Oyama F, Terada T, Shirouzu M, Sekine SI, Nukina N, Yokoyama S. Shimizu H, et al. Among authors: shirouzu m. J Biol Chem. 2017 Aug 11;292(32):13428-13440. doi: 10.1074/jbc.M117.786509. Epub 2017 Jun 27. J Biol Chem. 2017. PMID: 28655765 Free PMC article.
Gilteritinib overcomes lorlatinib resistance in ALK-rearranged cancer.
Mizuta H, Okada K, Araki M, Adachi J, Takemoto A, Kutkowska J, Maruyama K, Yanagitani N, Oh-Hara T, Watanabe K, Tamai K, Friboulet L, Katayama K, Ma B, Sasakura Y, Sagae Y, Kukimoto-Niino M, Shirouzu M, Takagi S, Simizu S, Nishio M, Okuno Y, Fujita N, Katayama R. Mizuta H, et al. Among authors: shirouzu m. Nat Commun. 2021 Feb 24;12(1):1261. doi: 10.1038/s41467-021-21396-w. Nat Commun. 2021. PMID: 33627640 Free PMC article.
Kastor and Polluks polypeptides encoded by a single gene locus cooperatively regulate VDAC and spermatogenesis.
Mise S, Matsumoto A, Shimada K, Hosaka T, Takahashi M, Ichihara K, Shimizu H, Shiraishi C, Saito D, Suyama M, Yasuda T, Ide T, Izumi Y, Bamba T, Kimura-Someya T, Shirouzu M, Miyata H, Ikawa M, Nakayama KI. Mise S, et al. Among authors: shirouzu m. Nat Commun. 2022 Feb 28;13(1):1071. doi: 10.1038/s41467-022-28677-y. Nat Commun. 2022. PMID: 35228556 Free PMC article.
432 results