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CN128: A New Orally Active Hydroxypyridinone Iron Chelator.
Chen W, Yuan X, Li Z, Lu Z, Kong S, Jiang H, Du H, Pan X, Nandi M, Kong X, Brown K, Liu Z, Zhang G, Hider RC, Yu Y. Chen W, et al. Among authors: brown k. J Med Chem. 2020 Apr 23;63(8):4215-4226. doi: 10.1021/acs.jmedchem.0c00137. Epub 2020 Apr 2. J Med Chem. 2020. PMID: 32208614
Discovery and clinical evaluation of 1-{N-[2-(amidinoaminooxy)ethyl]amino}carbonylmethyl-6-methyl-3-[2,2-difluoro-2-phenylethylamino]pyrazinone (RWJ-671818), a thrombin inhibitor with an oxyguanidine P1 motif.
Lu T, Markotan T, Ballentine SK, Giardino EC, Spurlino J, Crysler CS, Brown K, Maryanoff BE, Tomczuk BE, Damiano BP, Shukla U, End D, Andrade-Gordon P, Bone RF, Player MR. Lu T, et al. Among authors: brown k. J Med Chem. 2010 Feb 25;53(4):1843-56. doi: 10.1021/jm901802n. J Med Chem. 2010. PMID: 20102150 Clinical Trial.
Apical Suspension Repair for Vaginal Vault Prolapse: A Randomized Clinical Trial.
Menefee SA, Richter HE, Myers D, Moalli P, Weidner AC, Harvie HS, Rahn DD, Meriwether KV, Paraiso MFR, Whitworth R, Mazloomdoost D, Thomas S; NICHD Pelvic Floor Disorders Network. Menefee SA, et al. JAMA Surg. 2024 May 22. doi: 10.1001/jamasurg.2024.1206. Online ahead of print. JAMA Surg. 2024. PMID: 38776067
Enhanced CD95 and interleukin 18 signalling accompany T cell receptor Vβ21.3+ activation in multi-inflammatory syndrome in children.
Zhang Z, Kean IRL, Dratva LM, Clark JA, Syrimi E, Khan N, Daubney E, White D, O'Neill L, Chisholm C, Payne C, Benkenstein S, Kupiec K, Galassini R, Wright V, Winmill H, Robbins C, Brown K, Ramnarayan P, Scholefield B, Peters M, Klein N, Montgomery H, Meyer KB, Teichmann SA, Bryant C, Taylor G, Pathan N. Zhang Z, et al. Among authors: brown k. Nat Commun. 2024 May 18;15(1):4227. doi: 10.1038/s41467-024-48699-y. Nat Commun. 2024. PMID: 38762592 Free PMC article.
Association between infectious diseases consultation and mortality in hospitalized patients with Gram-negative bloodstream infection: a retrospective population-wide cohort study.
Ong SWX, Luo J, Fridman DJ, Lee SM, Johnstone J, Schwartz KL, Diong C, Patel SN, MacFadden DR, Langford BJ, Tong SYC, Brown KA, Daneman N. Ong SWX, et al. Among authors: brown ka. Clin Infect Dis. 2024 May 17:ciae282. doi: 10.1093/cid/ciae282. Online ahead of print. Clin Infect Dis. 2024. PMID: 38758977
8,686 results