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Enhancing the expression and function of an EBV-TCR on engineered T cells by combining Sc-TCR design with CRISPR editing to prevent mispairing.
Xue SA, Chen Y, Voss RH, Kisan V, Wang B, Chen KK, He FQ, Cheng XX, Scolamiero L, Holler A, Gao L, Morris E, Stauss HJ. Xue SA, et al. Among authors: holler a. Cell Mol Immunol. 2020 Dec;17(12):1275-1277. doi: 10.1038/s41423-020-0396-9. Epub 2020 Mar 17. Cell Mol Immunol. 2020. PMID: 32203185 Free PMC article. No abstract available.
Monoclonal T-cell receptors: new reagents for cancer therapy.
Stauss HJ, Cesco-Gaspere M, Thomas S, Hart DP, Xue SA, Holler A, Wright G, Perro M, Little AM, Pospori C, King J, Morris EC. Stauss HJ, et al. Among authors: holler a. Mol Ther. 2007 Oct;15(10):1744-50. doi: 10.1038/sj.mt.6300216. Epub 2007 Jul 17. Mol Ther. 2007. PMID: 17637721 Free article. Review.
CD3 limits the efficacy of TCR gene therapy in vivo.
Ahmadi M, King JW, Xue SA, Voisine C, Holler A, Wright GP, Waxman J, Morris E, Stauss HJ. Ahmadi M, et al. Among authors: holler a. Blood. 2011 Sep 29;118(13):3528-37. doi: 10.1182/blood-2011-04-346338. Epub 2011 Jul 12. Blood. 2011. PMID: 21750319 Free article.
CD8 T cell tolerance to a tumor-associated self-antigen is reversed by CD4 T cells engineered to express the same T cell receptor.
Ghorashian S, Veliça P, Chua I, McNicol AM, Carpenter B, Holler A, Nicholson E, Ahmadi M, Zech M, Xue SA, Uckert W, Morris E, Chakraverty R, Stauss HJ. Ghorashian S, et al. Among authors: holler a. J Immunol. 2015 Feb 1;194(3):1080-9. doi: 10.4049/jimmunol.1401703. Epub 2014 Dec 24. J Immunol. 2015. PMID: 25539815 Free PMC article.
Engineering CD4+ T Cells to Enhance Cancer Immunity.
Sillito F, Holler A, Stauss HJ. Sillito F, et al. Among authors: holler a. Cells. 2020 Jul 18;9(7):1721. doi: 10.3390/cells9071721. Cells. 2020. PMID: 32708397 Free PMC article. Review.
Exploiting alloreactivity for tumour immunotherapy.
Stauss HJ, Xue S, Gillmore R, Gao L, Bendle G, Holler A, Downs AM, Morris E. Stauss HJ, et al. Among authors: holler a. Vox Sang. 2004 Jul;87 Suppl 2:227-9. doi: 10.1111/j.1741-6892.2004.00493.x. Vox Sang. 2004. PMID: 15209922 Review. No abstract available.
114 results