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Deficiency in the glycosyltransferase Gcnt1 increases susceptibility to tuberculosis through a mechanism involving neutrophils.
Fonseca KL, Maceiras AR, Matos R, Simoes-Costa L, Sousa J, Cá B, Barros L, Fernandes AI, Mereiter S, Reis R, Gomes J, Tapia G, Rodríguez-Martínez P, Martín-Céspedes M, Vashakidze S, Gogishvili S, Nikolaishvili K, Appelberg R, Gärtner F, Rodrigues PNS, Vilaplana C, Reis CA, Magalhães A, Saraiva M. Fonseca KL, et al. Among authors: simoes costa l. Mucosal Immunol. 2020 Sep;13(5):836-848. doi: 10.1038/s41385-020-0277-7. Epub 2020 Mar 13. Mucosal Immunol. 2020. PMID: 32203062 Free PMC article.
Mycobacterium tuberculosis associated with severe tuberculosis evades cytosolic surveillance systems and modulates IL-1β production.
Sousa J, Cá B, Maceiras AR, Simões-Costa L, Fonseca KL, Fernandes AI, Ramos A, Carvalho T, Barros L, Magalhães C, Chiner-Oms Á, Machado H, Veiga MI, Singh A, Pereira R, Amorim A, Vieira J, Vieira CP, Bhatt A, Rodrigues F, Rodrigues PNS, Gagneux S, Castro AG, Guimarães JT, Bastos HN, Osório NS, Comas I, Saraiva M. Sousa J, et al. Among authors: simoes costa l. Nat Commun. 2020 Apr 23;11(1):1949. doi: 10.1038/s41467-020-15832-6. Nat Commun. 2020. PMID: 32327653 Free PMC article.
Maternal vaccination against group B Streptococcus glyceraldehyde-3-phosphate dehydrogenase leads to gut dysbiosis in the offspring.
Bonifácio Andrade E, Lorga I, Roque S, Geraldo R, Mesquita P, Castro R, Simões-Costa L, Costa M, Faustino A, Ribeiro A, Correia-Neves M, Trieu-Cuot P, Ferreira P. Bonifácio Andrade E, et al. Among authors: simoes costa l. Brain Behav Immun. 2022 Jul;103:186-201. doi: 10.1016/j.bbi.2022.04.004. Epub 2022 Apr 12. Brain Behav Immun. 2022. PMID: 35427758