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Amelioration of elastase-induced lung emphysema and reversal of pulmonary hypertension by pharmacological iNOS inhibition in mice.
Fysikopoulos A, Seimetz M, Hadzic S, Knoepp F, Wu CY, Malkmus K, Wilhelm J, Pichl A, Bednorz M, Tadele Roxlau E, Ghofrani HA, Sommer N, Gierhardt M, Schermuly RT, Seeger W, Grimminger F, Weissmann N, Kraut S. Fysikopoulos A, et al. Among authors: grimminger f. Br J Pharmacol. 2021 Jan;178(1):152-171. doi: 10.1111/bph.15057. Epub 2020 Apr 28. Br J Pharmacol. 2021. PMID: 32201936 Free article.
Inducible NOS inhibition reverses tobacco-smoke-induced emphysema and pulmonary hypertension in mice.
Seimetz M, Parajuli N, Pichl A, Veit F, Kwapiszewska G, Weisel FC, Milger K, Egemnazarov B, Turowska A, Fuchs B, Nikam S, Roth M, Sydykov A, Medebach T, Klepetko W, Jaksch P, Dumitrascu R, Garn H, Voswinckel R, Kostin S, Seeger W, Schermuly RT, Grimminger F, Ghofrani HA, Weissmann N. Seimetz M, et al. Among authors: grimminger f. Cell. 2011 Oct 14;147(2):293-305. doi: 10.1016/j.cell.2011.08.035. Cell. 2011. PMID: 22000010 Free article.
Stimulation of soluble guanylate cyclase prevents cigarette smoke-induced pulmonary hypertension and emphysema.
Weissmann N, Lobo B, Pichl A, Parajuli N, Seimetz M, Puig-Pey R, Ferrer E, Peinado VI, Domínguez-Fandos D, Fysikopoulos A, Stasch JP, Ghofrani HA, Coll-Bonfill N, Frey R, Schermuly RT, García-Lucio J, Blanco I, Bednorz M, Tura-Ceide O, Tadele E, Brandes RP, Grimminger J, Klepetko W, Jaksch P, Rodriguez-Roisin R, Seeger W, Grimminger F, Barberà JA. Weissmann N, et al. Among authors: grimminger f, grimminger j. Am J Respir Crit Care Med. 2014 Jun 1;189(11):1359-73. doi: 10.1164/rccm.201311-2037OC. Am J Respir Crit Care Med. 2014. PMID: 24738736
Riociguat for treatment of pulmonary hypertension in COPD: a translational study.
Pichl A, Sommer N, Bednorz M, Seimetz M, Hadzic S, Kuhnert S, Kraut S, Roxlau ET, Kojonazarov B, Wilhelm J, Gredic M, Gall H, Tello K, Richter MJ, Pak O, Petrovic A, Hecker M, Schermuly RT, Grimminger F, Seeger W, Ghofrani HA, Weissmann N. Pichl A, et al. Among authors: grimminger f. Eur Respir J. 2019 Jun 27;53(6):1802445. doi: 10.1183/13993003.02445-2018. Print 2019 Jun. Eur Respir J. 2019. PMID: 30956210 Free article.
The effect of long-term doxycycline treatment in a mouse model of cigarette smoke-induced emphysema and pulmonary hypertension.
Hadzic S, Wu CY, Gredic M, Kojonazarov B, Pak O, Kraut S, Sommer N, Kosanovic D, Grimminger F, Schermuly RT, Seeger W, Bellusci S, Weissmann N. Hadzic S, et al. Among authors: grimminger f. Am J Physiol Lung Cell Mol Physiol. 2021 May 1;320(5):L903-L915. doi: 10.1152/ajplung.00048.2021. Epub 2021 Mar 24. Am J Physiol Lung Cell Mol Physiol. 2021. PMID: 33760647 Free article.
Myeloid-cell-specific deletion of inducible nitric oxide synthase protects against smoke-induced pulmonary hypertension in mice.
Gredic M, Wu CY, Hadzic S, Pak O, Savai R, Kojonazarov B, Doswada S, Weiss A, Weigert A, Guenther A, Brandes RP, Schermuly RT, Grimminger F, Seeger W, Sommer N, Kraut S, Weissmann N. Gredic M, et al. Among authors: grimminger f. Eur Respir J. 2022 Apr 7;59(4):2101153. doi: 10.1183/13993003.01153-2021. Print 2022 Apr. Eur Respir J. 2022. PMID: 34475225 Free PMC article.
Severe Emphysema in the SU5416/Hypoxia Rat Model of Pulmonary Hypertension.
Kojonazarov B, Hadzic S, Ghofrani HA, Grimminger F, Seeger W, Weissmann N, Schermuly RT. Kojonazarov B, et al. Among authors: grimminger f. Am J Respir Crit Care Med. 2019 Aug 15;200(4):515-518. doi: 10.1164/rccm.201902-0390LE. Am J Respir Crit Care Med. 2019. PMID: 31034778 No abstract available.
534 results