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Page 1
Amelioration of elastase-induced lung emphysema and reversal of pulmonary hypertension by pharmacological iNOS inhibition in mice.
Fysikopoulos A, Seimetz M, Hadzic S, Knoepp F, Wu CY, Malkmus K, Wilhelm J, Pichl A, Bednorz M, Tadele Roxlau E, Ghofrani HA, Sommer N, Gierhardt M, Schermuly RT, Seeger W, Grimminger F, Weissmann N, Kraut S. Fysikopoulos A, et al. Among authors: gierhardt m. Br J Pharmacol. 2021 Jan;178(1):152-171. doi: 10.1111/bph.15057. Epub 2020 Apr 28. Br J Pharmacol. 2021. PMID: 32201936 Free article.
Effects of dimethylarginine dimethylaminohydrolase-1 overexpression on the response of the pulmonary vasculature to hypoxia.
Bakr A, Pak O, Taye A, Hamada F, Hemeida R, Janssen W, Gierhardt M, Ghofrani HA, Seeger W, Grimminger F, Schermuly RT, Witzenrath M, Brandes RP, Huang N, Cooke JP, Weissmann N, Sommer N. Bakr A, et al. Among authors: gierhardt m. Am J Respir Cell Mol Biol. 2013 Sep;49(3):491-500. doi: 10.1165/rcmb.2012-0330OC. Am J Respir Cell Mol Biol. 2013. PMID: 23642043 Free PMC article.
Mitochondrial Complex IV Subunit 4 Isoform 2 Is Essential for Acute Pulmonary Oxygen Sensing.
Sommer N, Hüttemann M, Pak O, Scheibe S, Knoepp F, Sinkler C, Malczyk M, Gierhardt M, Esfandiary A, Kraut S, Jonas F, Veith C, Aras S, Sydykov A, Alebrahimdehkordi N, Giehl K, Hecker M, Brandes RP, Seeger W, Grimminger F, Ghofrani HA, Schermuly RT, Grossman LI, Weissmann N. Sommer N, et al. Among authors: gierhardt m. Circ Res. 2017 Aug 4;121(4):424-438. doi: 10.1161/CIRCRESAHA.116.310482. Epub 2017 Jun 15. Circ Res. 2017. PMID: 28620066 Free PMC article.
Impact of the mitochondria-targeted antioxidant MitoQ on hypoxia-induced pulmonary hypertension.
Pak O, Scheibe S, Esfandiary A, Gierhardt M, Sydykov A, Logan A, Fysikopoulos A, Veit F, Hecker M, Kroschel F, Quanz K, Erb A, Schäfer K, Fassbinder M, Alebrahimdehkordi N, Ghofrani HA, Schermuly RT, Brandes RP, Seeger W, Murphy MP, Weissmann N, Sommer N. Pak O, et al. Among authors: gierhardt m. Eur Respir J. 2018 Feb 1:1701024. doi: 10.1183/13993003.01024-2017. Online ahead of print. Eur Respir J. 2018. PMID: 29419444
Genetic deletion of p66shc and/or cyclophilin D results in decreased pulmonary vascular tone.
Gierhardt M, Pak O, Sydykov A, Kraut S, Schäffer J, Garcia C, Veith C, Zeidan EM, Brosien M, Quanz K, Esfandiary A, Saraji A, Hadzic S, Kojonazarov B, Wilhelm J, Ghofrani HA, Schermuly RT, Seeger W, Grimminger F, Herden C, Schulz R, Weissmann N, Heger J, Sommer N. Gierhardt M, et al. Cardiovasc Res. 2022 Jan 7;118(1):305-315. doi: 10.1093/cvr/cvaa310. Cardiovasc Res. 2022. PMID: 33119054 Free PMC article.
Decreased plasma levels of the brain-derived neurotrophic factor correlate with right heart congestion in pulmonary arterial hypertension.
Schäfer K, Tello K, Pak O, Richter M, Gierhardt M, Kwapiszewska G, Veith C, Fink L, Gall H, Hecker M, Kojonazarov B, Kraut S, Lo K, Wilhelm J, Grimminger F, Seeger W, Schermuly RT, Ghofrani HA, Zahner D, Gerstberger R, Weissmann N, Sydykov A, Sommer N. Schäfer K, et al. Among authors: gierhardt m. ERJ Open Res. 2023 Mar 6;9(2):00230-2022. doi: 10.1183/23120541.00230-2022. eCollection 2023 Mar. ERJ Open Res. 2023. PMID: 36891080 Free PMC article.
The Role of the Redox Enzyme p66Shc in Biological Aging of the Lung.
Castro CFG, Nardiello C, Hadzic S, Kojonazarov B, Kraut S, Gierhardt M, Schäffer J, Bednorz M, Quanz K, Heger J, Korfei M, Wilhelm J, Hecker M, Bartkuhn M, Arnhold S, Guenther A, Seeger W, Schulz R, Weissmann N, Sommer N, Pak O. Castro CFG, et al. Among authors: gierhardt m. Aging Dis. 2024 Apr 1;15(2):911-926. doi: 10.14336/AD.2023.0715. Aging Dis. 2024. PMID: 37548932 Free PMC article.