Bharadwaj U - Search Results

1

Targeting Janus Kinases and Signal Transducer and Activator of Transcription 3 to Treat Inflammation, Fibrosis, and Cancer: Rationale, Progress, and Caution.

Bharadwaj U, Kasembeli MM, Robinson P, Tweardy DJ. Bharadwaj U, et al. Pharmacol Rev. 2020 Apr;72(2):486-526. doi: 10.1124/pr.119.018440. Pharmacol Rev. 2020. PMID: 32198236 Free PMC article. Review.

2

Mesothelin-induced pancreatic cancer cell proliferation involves alteration of cyclin E via activation of signal transducer and activator of transcription protein 3.

Bharadwaj U, Li M, Chen C, Yao Q. Bharadwaj U, et al. Mol Cancer Res. 2008 Nov;6(11):1755-65. doi: 10.1158/1541-7786.MCR-08-0095. Mol Cancer Res. 2008. PMID: 19010822 Free PMC article.

3

A novel role of microRNA146b in promoting mammary alveolar progenitor cell maintenance.

Elsarraj HS, Hong Y, Valdez K, Carletti M, Salah SM, Raimo M, Taverna D, Prochasson P, Bharadwaj U, Tweardy DJ, Christenson LK, Behbod F. Elsarraj HS, et al. Among authors: bharadwaj u. J Cell Sci. 2013 Jun 1;126(Pt 11):2446-58. doi: 10.1242/jcs.119214. Epub 2013 Apr 9. J Cell Sci. 2013. PMID: 23572509 Free PMC article.

4

Drug-repositioning screening identified piperlongumine as a direct STAT3 inhibitor with potent activity against breast cancer.

Bharadwaj U, Eckols TK, Kolosov M, Kasembeli MM, Adam A, Torres D, Zhang X, Dobrolecki LE, Wei W, Lewis MT, Dave B, Chang JC, Landis MD, Creighton CJ, Mancini MA, Tweardy DJ. Bharadwaj U, et al. Oncogene. 2015 Mar 12;34(11):1341-53. doi: 10.1038/onc.2014.72. Epub 2014 Mar 31. Oncogene. 2015. PMID: 24681959 Free PMC article.

5

Monoclonal Antibodies Specific for STAT3β Reveal Its Contribution to Constitutive STAT3 Phosphorylation in Breast Cancer.

Bharadwaj U, Kasembeli MM, Eckols TK, Kolosov M, Lang P, Christensen K, Edwards DP, Tweardy DJ. Bharadwaj U, et al. Cancers (Basel). 2014 Sep 29;6(4):2012-34. doi: 10.3390/cancers6042012. Cancers (Basel). 2014. PMID: 25268166 Free PMC article.

6

Small-molecule targeting of signal transducer and activator of transcription (STAT) 3 to treat non-small cell lung cancer.

Lewis KM, Bharadwaj U, Eckols TK, Kolosov M, Kasembeli MM, Fridley C, Siller R, Tweardy DJ. Lewis KM, et al. Among authors: bharadwaj u. Lung Cancer. 2015 Nov;90(2):182-90. doi: 10.1016/j.lungcan.2015.09.014. Epub 2015 Sep 15. Lung Cancer. 2015. PMID: 26410177 Free PMC article.

7

Piperlongumine Blocks JAK2-STAT3 to Inhibit Collagen-Induced Platelet Reactivity Independent of Reactive Oxygen Species.

Yuan H, Houck KL, Tian Y, Bharadwaj U, Hull K, Zhou Z, Zhu M, Wu X, Tweardy DJ, Romo D, Fu X, Zhang Y, Zhang J, Dong JF. Yuan H, et al. Among authors: bharadwaj u. PLoS One. 2015 Dec 8;10(12):e0143964. doi: 10.1371/journal.pone.0143964. eCollection 2015. PLoS One. 2015. PMID: 26645674 Free PMC article.

8

Correction: Piperlongumine Blocks JAK2-STAT3 to Inhibit Collagen-Induced Platelet Reactivity Independent of Reactive Oxygen Species†.

Yuan H, Houck KL, Tian Y, Bharadwaj U, Hull K, Zhou Z, Zhu M, Wu X, Tweardy DJ, Romo D, Fu X, Zhang Y, Zhang J, Dong JF. Yuan H, et al. Among authors: bharadwaj u. PLoS One. 2016 Jan 4;11(1):e0146626. doi: 10.1371/journal.pone.0146626. eCollection 2016. PLoS One. 2016. PMID: 26727022 Free PMC article. No abstract available.

9

A mix of S and ΔS variants of STAT3 enable survival of activated B-cell-like diffuse large B-cell lymphoma cells in culture.

Zheng M, Turton KB, Zhu F, Li Y, Grindle KM, Annis DS, Lu L, Drennan AC, Tweardy DJ, Bharadwaj U, Mosher DF, Rui L. Zheng M, et al. Among authors: bharadwaj u. Oncogenesis. 2016 Jan 4;4(1):e184. doi: 10.1038/oncsis.2015.44. Oncogenesis. 2016. PMID: 26727576 Free PMC article.

10

Substance P Receptor Signaling Mediates Doxorubicin-Induced Cardiomyocyte Apoptosis and Triple-Negative Breast Cancer Chemoresistance.

Robinson P, Kasembeli M, Bharadwaj U, Engineer N, Eckols KT, Tweardy DJ. Robinson P, et al. Among authors: bharadwaj u. Biomed Res Int. 2016;2016:1959270. doi: 10.1155/2016/1959270. Epub 2016 Feb 11. Biomed Res Int. 2016. PMID: 26981525 Free PMC article.

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