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Systemic AAV9.LAMP2B injection reverses metabolic and physiologic multiorgan dysfunction in a murine model of Danon disease.
Manso AM, Hashem SI, Nelson BC, Gault E, Soto-Hermida A, Villarruel E, Brambatti M, Bogomolovas J, Bushway PJ, Chen C, Battiprolu P, Keravala A, Schwartz JD, Shah G, Gu Y, Dalton ND, Hammond K, Peterson K, Saftig P, Adler ED. Manso AM, et al. Among authors: peterson k. Sci Transl Med. 2020 Mar 18;12(535):eaax1744. doi: 10.1126/scitranslmed.aax1744. Sci Transl Med. 2020. PMID: 32188720
Impaired mitophagy facilitates mitochondrial damage in Danon disease.
Hashem SI, Murphy AN, Divakaruni AS, Klos ML, Nelson BC, Gault EC, Rowland TJ, Perry CN, Gu Y, Dalton ND, Bradford WH, Devaney EJ, Peterson KL, Jones KL, Taylor MRG, Chen J, Chi NC, Adler ED. Hashem SI, et al. J Mol Cell Cardiol. 2017 Jul;108:86-94. doi: 10.1016/j.yjmcc.2017.05.007. Epub 2017 May 16. J Mol Cell Cardiol. 2017. PMID: 28526246
Nesprin 1 is critical for nuclear positioning and anchorage.
Zhang J, Felder A, Liu Y, Guo LT, Lange S, Dalton ND, Gu Y, Peterson KL, Mizisin AP, Shelton GD, Lieber RL, Chen J. Zhang J, et al. Hum Mol Genet. 2010 Jan 15;19(2):329-41. doi: 10.1093/hmg/ddp499. Epub 2009 Oct 28. Hum Mol Genet. 2010. PMID: 19864491 Free PMC article.
Postnatal Loss of Kindlin-2 Leads to Progressive Heart Failure.
Zhang Z, Mu Y, Veevers J, Peter AK, Manso AM, Bradford WH, Dalton ND, Peterson KL, Knowlton KU, Ross RS, Zhou X, Chen J. Zhang Z, et al. Among authors: peterson kl. Circ Heart Fail. 2016 Aug;9(8):10.1161/CIRCHEARTFAILURE.116.003129 e003129. doi: 10.1161/CIRCHEARTFAILURE.116.003129. Circ Heart Fail. 2016. PMID: 27502369 Free PMC article.
Combinatorial interactions of genetic variants in human cardiomyopathy.
Deacon DC, Happe CL, Chen C, Tedeschi N, Manso AM, Li T, Dalton ND, Peng Q, Farah EN, Gu Y, Tenerelli KP, Tran VD, Chen J, Peterson KL, Schork NJ, Adler ED, Engler AJ, Ross RS, Chi NC. Deacon DC, et al. Nat Biomed Eng. 2019 Feb;3(2):147-157. doi: 10.1038/s41551-019-0348-9. Epub 2019 Feb 7. Nat Biomed Eng. 2019. PMID: 30923642 Free PMC article.
2,335 results