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Eomes broadens the scope of CD8 T-cell memory by inhibiting apoptosis in cells of low affinity.
Kavazović I, Han H, Balzaretti G, Slinger E, Lemmermann NAW, Ten Brinke A, Merkler D, Koster J, Bryceson YT, de Vries N, Jonjić S, Klarenbeek PL, Polić B, Eldering E, Wensveen FM. Kavazović I, et al. Among authors: merkler d. PLoS Biol. 2020 Mar 17;18(3):e3000648. doi: 10.1371/journal.pbio.3000648. eCollection 2020 Mar. PLoS Biol. 2020. PMID: 32182234 Free PMC article.
The alarmin interleukin-33 drives protective antiviral CD8⁺ T cell responses.
Bonilla WV, Fröhlich A, Senn K, Kallert S, Fernandez M, Johnson S, Kreutzfeldt M, Hegazy AN, Schrick C, Fallon PG, Klemenz R, Nakae S, Adler H, Merkler D, Löhning M, Pinschewer DD. Bonilla WV, et al. Among authors: merkler d. Science. 2012 Feb 24;335(6071):984-9. doi: 10.1126/science.1215418. Epub 2012 Feb 9. Science. 2012. PMID: 22323740
Profiling the specificity of clonally expanded plasma cells during chronic viral infection by single-cell analysis.
Neumeier D, Pedrioli A, Genovese A, Sandu I, Ehling R, Hong KL, Papadopoulou C, Agrafiotis A, Kuhn R, Shlesinger D, Robbiani D, Han J, Hauri L, Csepregi L, Greiff V, Merkler D, Reddy ST, Oxenius A, Yermanos A. Neumeier D, et al. Among authors: merkler d. Eur J Immunol. 2022 Feb;52(2):297-311. doi: 10.1002/eji.202149331. Epub 2021 Nov 23. Eur J Immunol. 2022. PMID: 34727578 Free PMC article.
Tissue-resident memory CD8+ T cells cooperate with CD4+ T cells to drive compartmentalized immunopathology in the CNS.
Vincenti I, Page N, Steinbach K, Yermanos A, Lemeille S, Nunez N, Kreutzfeldt M, Klimek B, Di Liberto G, Egervari K, Piccinno M, Shammas G, Mariotte A, Fonta N, Liaudet N, Shlesinger D, Liuzzi AR, Wagner I, Saadi C, Stadelmann C, Reddy S, Becher B, Merkler D. Vincenti I, et al. Among authors: merkler d. Sci Transl Med. 2022 Apr 13;14(640):eabl6058. doi: 10.1126/scitranslmed.abl6058. Epub 2022 Apr 13. Sci Transl Med. 2022. PMID: 35417190
253 results