James DC - Search Results

1

Cell function profiling to assess clone stability.

Dobson PD, Coss KP, Doherty C, Clifford J, Thompson B, James DC. Dobson PD, et al. Among authors: james dc. Biotechnol Bioeng. 2020 Jul;117(7):2295-2299. doi: 10.1002/bit.27336. Epub 2020 Apr 10. Biotechnol Bioeng. 2020. PMID: 32181887 Free PMC article.

2

Cell line-specific control of recombinant monoclonal antibody production by CHO cells.

O'Callaghan PM, McLeod J, Pybus LP, Lovelady CS, Wilkinson SJ, Racher AJ, Porter A, James DC. O'Callaghan PM, et al. Among authors: james dc. Biotechnol Bioeng. 2010 Aug 15;106(6):938-51. doi: 10.1002/bit.22769. Biotechnol Bioeng. 2010. PMID: 20589672

3

An empirical modeling platform to evaluate the relative control discrete CHO cell synthetic processes exert over recombinant monoclonal antibody production process titer.

McLeod J, O'Callaghan PM, Pybus LP, Wilkinson SJ, Root T, Racher AJ, James DC. McLeod J, et al. Among authors: james dc. Biotechnol Bioeng. 2011 Sep;108(9):2193-204. doi: 10.1002/bit.23146. Epub 2011 Apr 27. Biotechnol Bioeng. 2011. PMID: 21445882

4

A mechanistic understanding of production instability in CHO cell lines expressing recombinant monoclonal antibodies.

Kim M, O'Callaghan PM, Droms KA, James DC. Kim M, et al. Among authors: james dc. Biotechnol Bioeng. 2011 Oct;108(10):2434-46. doi: 10.1002/bit.23189. Epub 2011 May 19. Biotechnol Bioeng. 2011. PMID: 21538334

5

Impact of gene vector design on the control of recombinant monoclonal antibody production by Chinese hamster ovary cells.

Davies SL, O'Callaghan PM, McLeod J, Pybus LP, Sung YH, Rance J, Wilkinson SJ, Racher AJ, Young RJ, James DC. Davies SL, et al. Among authors: james dc. Biotechnol Prog. 2011 Nov-Dec;27(6):1689-99. doi: 10.1002/btpr.692. Epub 2011 Aug 31. Biotechnol Prog. 2011. PMID: 21882365

6

Cell line specific control of polyethylenimine-mediated transient transfection optimized with "Design of experiments" methodology.

Thompson BC, Segarra CR, Mozley OL, Daramola O, Field R, Levison PR, James DC. Thompson BC, et al. Among authors: james dc. Biotechnol Prog. 2012 Jan-Feb;28(1):179-87. doi: 10.1002/btpr.715. Epub 2011 Oct 14. Biotechnol Prog. 2012. PMID: 22002934

7

Functional heterogeneity and heritability in CHO cell populations.

Davies SL, Lovelady CS, Grainger RK, Racher AJ, Young RJ, James DC. Davies SL, et al. Among authors: james dc. Biotechnol Bioeng. 2013 Jan;110(1):260-74. doi: 10.1002/bit.24621. Epub 2012 Aug 16. Biotechnol Bioeng. 2013. PMID: 22833427

8

CHO cell line specific prediction and control of recombinant monoclonal antibody N-glycosylation.

Grainger RK, James DC. Grainger RK, et al. Among authors: james dc. Biotechnol Bioeng. 2013 Nov;110(11):2970-83. doi: 10.1002/bit.24959. Epub 2013 Jun 6. Biotechnol Bioeng. 2013. PMID: 23737295

9

Model-directed engineering of "difficult-to-express" monoclonal antibody production by Chinese hamster ovary cells.

Pybus LP, Dean G, West NR, Smith A, Daramola O, Field R, Wilkinson SJ, James DC. Pybus LP, et al. Among authors: james dc. Biotechnol Bioeng. 2014 Feb;111(2):372-85. doi: 10.1002/bit.25116. Epub 2013 Nov 14. Biotechnol Bioeng. 2014. PMID: 24081924

10

Synthetic promoters for CHO cell engineering.

Brown AJ, Sweeney B, Mainwaring DO, James DC. Brown AJ, et al. Among authors: james dc. Biotechnol Bioeng. 2014 Aug;111(8):1638-47. doi: 10.1002/bit.25227. Epub 2014 May 1. Biotechnol Bioeng. 2014. PMID: 24615264

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