Cassel T - Search Results

1

Regulation of hepatic glutamine metabolism by miR-122.

Sengupta D, Cassel T, Teng KY, Aljuhani M, Chowdhary VK, Hu P, Zhang X, Fan TW, Ghoshal K. Sengupta D, et al. Among authors: cassel t. Mol Metab. 2020 Apr;34:174-186. doi: 10.1016/j.molmet.2020.01.003. Epub 2020 Jan 9. Mol Metab. 2020. PMID: 32180557 Free PMC article.

2

Stable Isotope-Resolved Metabolomics Shows Metabolic Resistance to Anti-Cancer Selenite in 3D Spheroids versus 2D Cell Cultures.

Fan TW, El-Amouri SS, Macedo JKA, Wang QJ, Song H, Cassel T, Lane AN. Fan TW, et al. Among authors: cassel t. Metabolites. 2018 Jul 10;8(3):40. doi: 10.3390/metabo8030040. Metabolites. 2018. PMID: 29996515 Free PMC article.

3

Glutathione de novo synthesis but not recycling process coordinates with glutamine catabolism to control redox homeostasis and directs murine T cell differentiation.

Lian G, Gnanaprakasam JR, Wang T, Wu R, Chen X, Liu L, Shen Y, Yang M, Yang J, Chen Y, Vasiliou V, Cassel TA, Green DR, Liu Y, Fan TW, Wang R. Lian G, et al. Among authors: cassel ta. Elife. 2018 Sep 10;7:e36158. doi: 10.7554/eLife.36158. Elife. 2018. PMID: 30198844 Free PMC article.

4

JAK2-mutant hematopoietic cells display metabolic alterations that can be targeted to treat myeloproliferative neoplasms.

Rao TN, Hansen N, Hilfiker J, Rai S, Majewska JM, Leković D, Gezer D, Andina N, Galli S, Cassel T, Geier F, Delezie J, Nienhold R, Hao-Shen H, Beisel C, Di Palma S, Dimeloe S, Trebicka J, Wolf D, Gassmann M, Fan TW, Lane AN, Handschin C, Dirnhofer S, Kröger N, Hess C, Radimerski T, Koschmieder S, Čokić VP, Skoda RC. Rao TN, et al. Among authors: cassel t. Blood. 2019 Nov 21;134(21):1832-1846. doi: 10.1182/blood.2019000162. Blood. 2019. PMID: 31511238 Free PMC article.

5

Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase.

Palmieri EM, Gonzalez-Cotto M, Baseler WA, Davies LC, Ghesquière B, Maio N, Rice CM, Rouault TA, Cassel T, Higashi RM, Lane AN, Fan TW, Wink DA, McVicar DW. Palmieri EM, et al. Among authors: cassel t. Nat Commun. 2020 Feb 4;11(1):698. doi: 10.1038/s41467-020-14433-7. Nat Commun. 2020. PMID: 32019928 Free PMC article.

6

A negative reciprocal regulatory axis between cyclin D1 and HNF4α modulates cell cycle progression and metabolism in the liver.

Wu H, Reizel T, Wang YJ, Lapiro JL, Kren BT, Schug J, Rao S, Morgan A, Herman A, Shekels LL, Rassette MS, Lane AN, Cassel T, Fan TWM, Manivel JC, Gunewardena S, Apte U, Sicinski P, Kaestner KH, Albrecht JH. Wu H, et al. Among authors: cassel t. Proc Natl Acad Sci U S A. 2020 Jul 21;117(29):17177-17186. doi: 10.1073/pnas.2002898117. Epub 2020 Jul 6. Proc Natl Acad Sci U S A. 2020. PMID: 32631996 Free PMC article.

7

Inosine is an alternative carbon source for CD8⁺-T-cell function under glucose restriction.

Wang T, Gnanaprakasam JNR, Chen X, Kang S, Xu X, Sun H, Liu L, Rodgers H, Miller E, Cassel TA, Sun Q, Vicente-Muñoz S, Warmoes MO, Lin P, Piedra-Quintero ZL, Guerau-de-Arellano M, Cassady KA, Zheng SG, Yang J, Lane AN, Song X, Fan TW, Wang R. Wang T, et al. Among authors: cassel ta. Nat Metab. 2020 Jul;2(7):635-647. doi: 10.1038/s42255-020-0219-4. Epub 2020 Jun 15. Nat Metab. 2020. PMID: 32694789 Free PMC article.

8

Fumarate hydratase-deficient renal cell carcinoma cells respond to asparagine by activation of the unfolded protein response and stimulation of the hexosamine biosynthetic pathway.

Panarsky R, Crooks DR, Lane AN, Yang Y, Cassel TA, Fan TW, Linehan WM, Moscow JA. Panarsky R, et al. Cancer Metab. 2020 Aug 3;8:7. doi: 10.1186/s40170-020-00214-9. eCollection 2020. Cancer Metab. 2020. PMID: 32774853 Free PMC article.

9

Blockade of 6-phosphogluconate dehydrogenase generates CD8⁺ effector T cells with enhanced anti-tumor function.

Daneshmandi S, Cassel T, Lin P, Higashi RM, Wulf GM, Boussiotis VA, Fan TW, Seth P. Daneshmandi S, et al. Among authors: cassel t. Cell Rep. 2021 Mar 9;34(10):108831. doi: 10.1016/j.celrep.2021.108831. Cell Rep. 2021. PMID: 33691103 Free PMC article.

10

In vivo deep network tracing reveals phosphofructokinase-mediated coordination of biosynthetic pathway activity in the myocardium.

Fulghum KL, Audam TN, Lorkiewicz PK, Zheng Y, Merchant M, Cummins TD, Dean WL, Cassel TA, Fan TWM, Hill BG. Fulghum KL, et al. Among authors: cassel ta. J Mol Cell Cardiol. 2022 Jan;162:32-42. doi: 10.1016/j.yjmcc.2021.08.013. Epub 2021 Sep 3. J Mol Cell Cardiol. 2022. PMID: 34487754 Free PMC article.

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