Heasley LE - Search Results

1

Cancer Cell-Intrinsic Expression of MHC Class II Regulates the Immune Microenvironment and Response to Anti-PD-1 Therapy in Lung Adenocarcinoma.

Johnson AM, Bullock BL, Neuwelt AJ, Poczobutt JM, Kaspar RE, Li HY, Kwak JW, Hopp K, Weiser-Evans MCM, Heasley LE, Schenk EL, Clambey ET, Nemenoff RA. Johnson AM, et al. Among authors: heasley le. J Immunol. 2020 Apr 15;204(8):2295-2307. doi: 10.4049/jimmunol.1900778. Epub 2020 Mar 16. J Immunol. 2020. PMID: 32179637 Free PMC article.

2

Tyrosine kinase growth factor receptors but not seven-membrane-spanning receptors or phorbol esters activate mitogen-activated protein kinase in rat hepatocytes.

Ginès P, Li X, Zamarripa JL, Brown SE, Wieder ED, Nakamura T, Guzelian PS, Schrier RW, Heasley LE, Nemenoff RA. Ginès P, et al. Among authors: heasley le. Hepatology. 1995 Oct;22(4 Pt 1):1296-303. Hepatology. 1995. PMID: 7557884

3

Expression of a mutant Gi2 alpha subunit inhibits ATP and thrombin stimulation of cytoplasmic phospholipase A2-mediated arachidonic acid release independent of Ca2+ and mitogen-activated protein kinase regulation.

Winitz S, Gupta SK, Qian NX, Heasley LE, Nemenoff RA, Johnson GL. Winitz S, et al. Among authors: heasley le. J Biol Chem. 1994 Jan 21;269(3):1889-95. J Biol Chem. 1994. PMID: 8294438 Free article.

4

Phosphorylation and activation of a high molecular weight form of phospholipase A2 by p42 microtubule-associated protein 2 kinase and protein kinase C.

Nemenoff RA, Winitz S, Qian NX, Van Putten V, Johnson GL, Heasley LE. Nemenoff RA, et al. Among authors: heasley le. J Biol Chem. 1993 Jan 25;268(3):1960-4. J Biol Chem. 1993. PMID: 8380583 Free article.

5

Inhibitory actions of cyclic adenosine monophosphate and pertussis toxin define two distinct epidermal growth factor-regulated pathways leading to activation of mitogen-activated protein kinase in rat hepatocytes.

Ginès P, Li X, Brown SE, Nakamura T, Guzelian PS, Heasley LE, Schrier RW, Nemenoff RA. Ginès P, et al. Among authors: heasley le. Hepatology. 1996 May;23(5):1167-73. doi: 10.1002/hep.510230535. Hepatology. 1996. PMID: 8621150

6

Induction of cytosolic phospholipase A2 by oncogenic Ras in human non-small cell lung cancer.

Heasley LE, Thaler S, Nicks M, Price B, Skorecki K, Nemenoff RA. Heasley LE, et al. J Biol Chem. 1997 Jun 6;272(23):14501-4. doi: 10.1074/jbc.272.23.14501. J Biol Chem. 1997. PMID: 9169405 Free article.

7

Galpha16 mimics vasoconstrictor action to induce smooth muscle alpha-actin in vascular smooth muscle cells through a Jun-NH2-terminal kinase-dependent pathway.

Higashita R, Li L, Van Putten V, Yamamura Y, Zarinetchi F, Heasley L, Nemenoff RA. Higashita R, et al. J Biol Chem. 1997 Oct 10;272(41):25845-50. doi: 10.1074/jbc.272.41.25845. J Biol Chem. 1997. PMID: 9325315 Free article.

8

Suppression of smooth-muscle alpha-actin expression by platelet-derived growth factor in vascular smooth-muscle cells involves Ras and cytosolic phospholipase A2.

Li X, Van Putten V, Zarinetchi F, Nicks ME, Thaler S, Heasley LE, Nemenoff RA. Li X, et al. Among authors: heasley le. Biochem J. 1997 Nov 1;327 ( Pt 3)(Pt 3):709-16. doi: 10.1042/bj3270709. Biochem J. 1997. PMID: 9581546 Free PMC article.

9

Induction of cytosolic phospholipase A2 by oncogenic Ras is mediated through the JNK and ERK pathways in rat epithelial cells.

Van Putten V, Refaat Z, Dessev C, Blaine S, Wick M, Butterfield L, Han SY, Heasley LE, Nemenoff RA. Van Putten V, et al. Among authors: heasley le. J Biol Chem. 2001 Jan 12;276(2):1226-32. doi: 10.1074/jbc.M003581200. J Biol Chem. 2001. PMID: 11042196 Free article.

10

Peroxisome proliferator-activated receptor-gamma is a target of nonsteroidal anti-inflammatory drugs mediating cyclooxygenase-independent inhibition of lung cancer cell growth.

Wick M, Hurteau G, Dessev C, Chan D, Geraci MW, Winn RA, Heasley LE, Nemenoff RA. Wick M, et al. Among authors: heasley le. Mol Pharmacol. 2002 Nov;62(5):1207-14. doi: 10.1124/mol.62.5.1207. Mol Pharmacol. 2002. PMID: 12391285

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