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Saraf-dependent activation of mTORC1 regulates cardiac growth.
Sanlialp A, Schumacher D, Kiper L, Varma E, Riechert E, Ho TC, Hofmann C, Kmietczyk V, Zimmermann F, Dlugosz S, Wirth A, Gorska AA, Burghaus J, Camacho Londoño JE, Katus HA, Doroudgar S, Freichel M, Völkers M. Sanlialp A, et al. Among authors: wirth a. J Mol Cell Cardiol. 2020 Apr;141:30-42. doi: 10.1016/j.yjmcc.2020.03.004. Epub 2020 Mar 13. J Mol Cell Cardiol. 2020. PMID: 32173353
Novel Nongenetic Murine Model of Hyperglycemia and Hyperlipidemia-Associated Aggravated Atherosclerosis.
Gaul S, Shahzad K, Medert R, Gadi I, Mäder C, Schumacher D, Wirth A, Ambreen S, Fatima S, Boeckel JN, Khawaja H, Haas J, Brune M, Nawroth PP, Isermann B, Laufs U, Freichel M. Gaul S, et al. Among authors: wirth a. Front Cardiovasc Med. 2022 Mar 8;9:813215. doi: 10.3389/fcvm.2022.813215. eCollection 2022. Front Cardiovasc Med. 2022. PMID: 35350534 Free PMC article.
Deletion of the last five C-terminal amino acid residues of connexin43 leads to lethal ventricular arrhythmias in mice without affecting coupling via gap junction channels.
Lübkemeier I, Requardt RP, Lin X, Sasse P, Andrié R, Schrickel JW, Chkourko H, Bukauskas FF, Kim JS, Frank M, Malan D, Zhang J, Wirth A, Dobrowolski R, Mohler PJ, Offermanns S, Fleischmann BK, Delmar M, Willecke K. Lübkemeier I, et al. Among authors: wirth a. Basic Res Cardiol. 2013 May;108(3):348. doi: 10.1007/s00395-013-0348-y. Epub 2013 Apr 5. Basic Res Cardiol. 2013. PMID: 23558439 Free PMC article.
Helix 8 is the essential structural motif of mechanosensitive GPCRs.
Erdogmus S, Storch U, Danner L, Becker J, Winter M, Ziegler N, Wirth A, Offermanns S, Hoffmann C, Gudermann T, Mederos Y Schnitzler M. Erdogmus S, et al. Among authors: wirth a. Nat Commun. 2019 Dec 19;10(1):5784. doi: 10.1038/s41467-019-13722-0. Nat Commun. 2019. PMID: 31857598 Free PMC article.
Anaphylactic shock depends on endothelial Gq/G11.
Korhonen H, Fisslthaler B, Moers A, Wirth A, Habermehl D, Wieland T, Schütz G, Wettschureck N, Fleming I, Offermanns S. Korhonen H, et al. Among authors: wirth a. J Exp Med. 2009 Feb 16;206(2):411-20. doi: 10.1084/jem.20082150. Epub 2009 Jan 26. J Exp Med. 2009. PMID: 19171764 Free PMC article.
521 results