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Hypoxia-dependent modification of collagen networks promotes sarcoma metastasis.
Eisinger-Mathason TS, Zhang M, Qiu Q, Skuli N, Nakazawa MS, Karakasheva T, Mucaj V, Shay JE, Stangenberg L, Sadri N, Puré E, Yoon SS, Kirsch DG, Simon MC. Eisinger-Mathason TS, et al. Cancer Discov. 2013 Oct;3(10):1190-205. doi: 10.1158/2159-8290.CD-13-0118. Epub 2013 Aug 1. Cancer Discov. 2013. PMID: 23906982 Free PMC article.
Inhibition of vascular endothelial growth factor A and hypoxia-inducible factor 1α maximizes the effects of radiation in sarcoma mouse models through destruction of tumor vasculature.
Lee HJ, Yoon C, Park DJ, Kim YJ, Schmidt B, Lee YJ, Tap WD, Eisinger-Mathason TS, Choy E, Kirsch DG, Simon MC, Yoon SS. Lee HJ, et al. Int J Radiat Oncol Biol Phys. 2015 Mar 1;91(3):621-30. doi: 10.1016/j.ijrobp.2014.10.047. Epub 2014 Dec 24. Int J Radiat Oncol Biol Phys. 2015. PMID: 25544668 Free PMC article.
Intratumoral oxygen gradients mediate sarcoma cell invasion.
Lewis DM, Park KM, Tang V, Xu Y, Pak K, Eisinger-Mathason TS, Simon MC, Gerecht S. Lewis DM, et al. Proc Natl Acad Sci U S A. 2016 Aug 16;113(33):9292-7. doi: 10.1073/pnas.1605317113. Epub 2016 Aug 2. Proc Natl Acad Sci U S A. 2016. PMID: 27486245 Free PMC article.
34 results