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Neutrophil elastase degrades cystic fibrosis transmembrane conductance regulator via calpains and disables channel function in vitro and in vivo.
Le Gars M, Descamps D, Roussel D, Saussereau E, Guillot L, Ruffin M, Tabary O, Hong SS, Boulanger P, Paulais M, Malleret L, Belaaouaj A, Edelman A, Huerre M, Chignard M, Sallenave JM. Le Gars M, et al. Among authors: ruffin m. Am J Respir Crit Care Med. 2013 Jan 15;187(2):170-9. doi: 10.1164/rccm.201205-0875OC. Epub 2012 Dec 6. Am J Respir Crit Care Med. 2013. PMID: 23220915
Anoctamin 1 dysregulation alters bronchial epithelial repair in cystic fibrosis.
Ruffin M, Voland M, Marie S, Bonora M, Blanchard E, Blouquit-Laye S, Naline E, Puyo P, Le Rouzic P, Guillot L, Corvol H, Clement A, Tabary O. Ruffin M, et al. Biochim Biophys Acta. 2013 Dec;1832(12):2340-51. doi: 10.1016/j.bbadis.2013.09.012. Epub 2013 Sep 27. Biochim Biophys Acta. 2013. PMID: 24080196 Free article.
New insights about miRNAs in cystic fibrosis.
Sonneville F, Ruffin M, Guillot L, Rousselet N, Le Rouzic P, Corvol H, Tabary O. Sonneville F, et al. Among authors: ruffin m. Am J Pathol. 2015 Apr;185(4):897-908. doi: 10.1016/j.ajpath.2014.12.022. Epub 2015 Feb 14. Am J Pathol. 2015. PMID: 25687559 Free article. Review.
300 results