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Mice deficient in GM1 manifest both motor and non-motor symptoms of Parkinson's disease; successful treatment with synthetic GM1 ganglioside.
Exp Neurol. 2020 Jul;329:113284. doi: 10.1016/j.expneurol.2020.113284. Epub 2020 Mar 9.
Exp Neurol. 2020.
PMID: 32165255
Parkinson's disease recovery by GM1 oligosaccharide treatment in the B4galnt1+/- mouse model.
Chiricozzi E, Mauri L, Lunghi G, Di Biase E, Fazzari M, Maggioni M, Valsecchi M, Prioni S, Loberto N, Pomè DY, Ciampa MG, Fato P, Verlengia G, Cattaneo S, Assini R, Wu G, Alselehdar S, Ledeen RW, Sonnino S.
Chiricozzi E, et al.
Sci Rep. 2019 Dec 18;9(1):19330. doi: 10.1038/s41598-019-55885-2.
Sci Rep. 2019.
PMID: 31852959
Free PMC article.
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Subnormal GM1 in PBMCs: Promise for Early Diagnosis of Parkinson's Disease?
Alselehdar SK, Chakraborty M, Chowdhury S, Alcalay RN, Surface M, Ledeen R.
Alselehdar SK, et al.
Int J Mol Sci. 2021 Oct 26;22(21):11522. doi: 10.3390/ijms222111522.
Int J Mol Sci. 2021.
PMID: 34768952
Free PMC article.
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Direct and indirect pathways of the basal ganglia: opponents or collaborators?
Wang KS, McClure JP Jr, Alselehdar SK, Kanta V.
Wang KS, et al. Among authors: alselehdar sk.
Front Neuroanat. 2015 Mar 2;9:20. doi: 10.3389/fnana.2015.00020. eCollection 2015.
Front Neuroanat. 2015.
PMID: 25784859
Free PMC article.
No abstract available.
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