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Dendritic cells dictate responses to PD-L1 blockade cancer immunotherapy.
Mayoux M, Roller A, Pulko V, Sammicheli S, Chen S, Sum E, Jost C, Fransen MF, Buser RB, Kowanetz M, Rommel K, Matos I, Colombetti S, Belousov A, Karanikas V, Ossendorp F, Hegde PS, Chen DS, Umana P, Perro M, Klein C, Xu W. Mayoux M, et al. Among authors: jost c. Sci Transl Med. 2020 Mar 11;12(534):eaav7431. doi: 10.1126/scitranslmed.aav7431. Sci Transl Med. 2020. PMID: 32161104
Chimeric antigen receptor T cells engineered to recognize the P329G-mutated Fc part of effector-silenced tumor antigen-targeting human IgG1 antibodies enable modular targeting of solid tumors.
Stock S, Benmebarek MR, Kluever AK, Darowski D, Jost C, Stubenrauch KG, Benz J, Freimoser-Grundschober A, Moessner E, Umana P, Subklewe M, Endres S, Klein C, Kobold S. Stock S, et al. Among authors: jost c. J Immunother Cancer. 2022 Jul;10(7):e005054. doi: 10.1136/jitc-2022-005054. J Immunother Cancer. 2022. PMID: 35902133 Free PMC article.
Proteolysis-Targeting Chimeras Enhance T Cell Bispecific Antibody-Driven T Cell Activation and Effector Function through Increased MHC Class I Antigen Presentation in Cancer Cells.
Massafra V, Tundo S, Dietzig A, Ducret A, Jost C, Klein C, Kontermann RE, Knoetgen H, Steegmaier M, Romagnani A, Nagel YA. Massafra V, et al. Among authors: jost c. J Immunol. 2021 Jul 15;207(2):493-504. doi: 10.4049/jimmunol.2000252. Epub 2021 Jul 2. J Immunol. 2021. PMID: 34215653
214 results