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Intravenous administration of Reolysin, a live replication competent RNA virus is safe in patients with advanced solid tumors.
Gollamudi R, Ghalib MH, Desai KK, Chaudhary I, Wong B, Einstein M, Coffey M, Gill GM, Mettinger K, Mariadason JM, Mani S, Goel S. Gollamudi R, et al. Among authors: coffey m. Invest New Drugs. 2010 Oct;28(5):641-9. doi: 10.1007/s10637-009-9279-8. Epub 2009 Jul 2. Invest New Drugs. 2010. PMID: 19572105 Free PMC article. Clinical Trial.
Oncolytic viral therapy for prostate cancer: efficacy of reovirus as a biological therapeutic.
Thirukkumaran CM, Nodwell MJ, Hirasawa K, Shi ZQ, Diaz R, Luider J, Johnston RN, Forsyth PA, Magliocco AM, Lee P, Nishikawa S, Donnelly B, Coffey M, Trpkov K, Fonseca K, Spurrell J, Morris DG. Thirukkumaran CM, et al. Among authors: coffey m. Cancer Res. 2010 Mar 15;70(6):2435-44. doi: 10.1158/0008-5472.CAN-09-2408. Epub 2010 Mar 9. Cancer Res. 2010. PMID: 20215509
The oncolytic virus, pelareorep, as a novel anticancer agent: a review.
Chakrabarty R, Tran H, Selvaggi G, Hagerman A, Thompson B, Coffey M. Chakrabarty R, et al. Among authors: coffey m. Invest New Drugs. 2015 Jun;33(3):761-74. doi: 10.1007/s10637-015-0216-8. Epub 2015 Feb 19. Invest New Drugs. 2015. PMID: 25693885 Review.
Oncolytic reovirus in combination with chemotherapy in metastatic or recurrent non-small cell lung cancer patients with KRAS-activated tumors.
Villalona-Calero MA, Lam E, Otterson GA, Zhao W, Timmons M, Subramaniam D, Hade EM, Gill GM, Coffey M, Selvaggi G, Bertino E, Chao B, Knopp MV. Villalona-Calero MA, et al. Among authors: coffey m. Cancer. 2016 Mar 15;122(6):875-83. doi: 10.1002/cncr.29856. Epub 2015 Dec 28. Cancer. 2016. PMID: 26709987 Free PMC article.
A phase II study of REOLYSIN® (pelareorep) in combination with carboplatin and paclitaxel for patients with advanced malignant melanoma.
Mahalingam D, Fountzilas C, Moseley J, Noronha N, Tran H, Chakrabarty R, Selvaggi G, Coffey M, Thompson B, Sarantopoulos J. Mahalingam D, et al. Among authors: coffey m. Cancer Chemother Pharmacol. 2017 Apr;79(4):697-703. doi: 10.1007/s00280-017-3260-6. Epub 2017 Mar 13. Cancer Chemother Pharmacol. 2017. PMID: 28289863 Clinical Trial.
739 results