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Structure-Based Design and Discovery of New M2 Receptor Agonists.
Fish I, Stößel A, Eitel K, Valant C, Albold S, Huebner H, Möller D, Clark MJ, Sunahara RK, Christopoulos A, Shoichet BK, Gmeiner P. Fish I, et al. Among authors: huebner h. J Med Chem. 2017 Nov 22;60(22):9239-9250. doi: 10.1021/acs.jmedchem.7b01113. Epub 2017 Nov 13. J Med Chem. 2017. PMID: 29094937 Free PMC article.
Therapeutic antagonism of the neurokinin 1 receptor in endosomes provides sustained pain relief.
Hegron A, Peach CJ, Tonello R, Seemann P, Teng S, Latorre R, Huebner H, Weikert D, Rientjes J, Veldhuis NA, Poole DP, Jensen DD, Thomsen ARB, Schmidt BL, Imlach WL, Gmeiner P, Bunnett NW. Hegron A, et al. Among authors: huebner h. Proc Natl Acad Sci U S A. 2023 May 30;120(22):e2220979120. doi: 10.1073/pnas.2220979120. Epub 2023 May 22. Proc Natl Acad Sci U S A. 2023. PMID: 37216510 Free PMC article.
A new D₂ dopamine receptor agonist allosterically modulates A(2A) adenosine receptor signalling by interacting with the A(2A)/D₂ receptor heteromer.
Trincavelli ML, Daniele S, Orlandini E, Navarro G, Casadó V, Giacomelli C, Nencetti S, Nuti E, Macchia M, Huebner H, Gmeiner P, Rossello A, Lluís C, Martini C. Trincavelli ML, et al. Among authors: huebner h. Cell Signal. 2012 Apr;24(4):951-60. doi: 10.1016/j.cellsig.2011.12.018. Epub 2011 Dec 30. Cell Signal. 2012. PMID: 22230688
CDK4/6 Inhibition - Therapy Sequences and the Quest to Find the Best Biomarkers - an Overview of Current Programs.
Schneeweiss A, Brucker SY, Huebner H, Volmer LL, Hack CC, Seitz K, Ruebner M, Heublein S, Thewes V, Lüftner D, Lux MP, Jurhasz-Böss I, Taran FA, Wimberger P, Anetsberger D, Beierlein M, Schmidt M, Radosa J, Müller V, Janni W, Rack B, Belleville E, Untch M, Thill M, Ditsch N, Aktas B, Nel I, Kolberg HC, Engerle T, Tesch H, Roos C, Budden C, Neubauer H, Hartkopf AD, Fehm TN, Fasching PA. Schneeweiss A, et al. Among authors: huebner h. Geburtshilfe Frauenheilkd. 2024 May 29;84(5):443-458. doi: 10.1055/a-2286-6066. eCollection 2024 May. Geburtshilfe Frauenheilkd. 2024. PMID: 38817598 Free PMC article.
Attrition in the First Three Therapy Lines in Patients with Advanced Breast Cancer in the German Real-World PRAEGNANT Registry.
Hartkopf AD, Walter CB, Kolberg HC, Hadji P, Tesch H, Fasching PA, Ettl J, Lüftner D, Wallwiener M, Müller V, Beckmann MW, Belleville E, Huebner H, Uhrig S, Goossens C, Link T, Hielscher C, Mundhenke C, Kurbacher C, Wuerstlein R, Untch M, Janni W, Taran FA, Michel LL, Lux MP, Wallwiener D, Brucker SY, Fehm TN, Häberle L, Schneeweiss A. Hartkopf AD, et al. Among authors: huebner h. Geburtshilfe Frauenheilkd. 2024 May 29;84(5):459-469. doi: 10.1055/a-2286-5372. eCollection 2024 May. Geburtshilfe Frauenheilkd. 2024. PMID: 38817595 Free PMC article.
Correction: Long-term Follow-up and Safety of Patients after an Upfront Therapy with Letrozole for Early Breast Cancer in Routine Clinical Care - The PreFace Study.
Hack CC, Maass N, Aktas B, Kümmel S, Thomssen C, Wolf C, Kolberg HC, Brucker C, Janni W, Dall P, Schneeweiss A, Marme F, Ruebner M, Theuser AK, Hofmann NM, Böhm S, Almstedt K, Kellner S, Nabieva N, Gass P, Sütterlin MW, Lück HJ, Schmatloch S, Kalder M, Uleer C, Juhasz-Böss I, Hanf V, Jackisch C, Müller V, Rack B, Belleville E, Wallwiener D, Rody A, Rauh C, Bayer CM, Uhrig S, Goossens C, Huebner H, Brucker SY, Häberle L, Fehm TN, Hein A, Fasching PA. Hack CC, et al. Among authors: huebner h. Geburtshilfe Frauenheilkd. 2024 Apr 30;84(2):e10. doi: 10.1055/a-2314-3693. eCollection 2024 Feb. Geburtshilfe Frauenheilkd. 2024. PMID: 38690326 Free PMC article.
105 results