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Page 1
Molecular changes associated with spinal cord aging.
Piekarz KM, Bhaskaran S, Sataranatarajan K, Street K, Premkumar P, Saunders D, Zalles M, Gulej R, Khademi S, Laurin J, Peelor R, Miller BF, Towner R, Van Remmen H. Piekarz KM, et al. Geroscience. 2020 Apr;42(2):765-784. doi: 10.1007/s11357-020-00172-6. Epub 2020 Mar 6. Geroscience. 2020. PMID: 32144690 Free PMC article.
Mitochondrial oxidative stress impairs contractile function but paradoxically increases muscle mass via fibre branching.
Ahn B, Ranjit R, Premkumar P, Pharaoh G, Piekarz KM, Matsuzaki S, Claflin DR, Riddle K, Judge J, Bhaskaran S, Satara Natarajan K, Barboza E, Wronowski B, Kinter M, Humphries KM, Griffin TM, Freeman WM, Richardson A, Brooks SV, Van Remmen H. Ahn B, et al. Among authors: piekarz km. J Cachexia Sarcopenia Muscle. 2019 Apr;10(2):411-428. doi: 10.1002/jcsm.12375. Epub 2019 Feb 1. J Cachexia Sarcopenia Muscle. 2019. PMID: 30706998 Free PMC article.
Molecular changes in transcription and metabolic pathways underlying muscle atrophy in the CuZnSOD null mouse model of sarcopenia.
Sataranatarajan K, Pharaoh G, Brown JL, Ranjit R, Piekarz KM, Street K, Wren JD, Georgescu C, Kinter C, Kinter M, Freeman WM, Richardson A, Van Remmen H. Sataranatarajan K, et al. Among authors: piekarz km. Geroscience. 2020 Aug;42(4):1101-1118. doi: 10.1007/s11357-020-00189-x. Epub 2020 May 12. Geroscience. 2020. PMID: 32394347 Free PMC article.
Neuron-specific deletion of CuZnSOD leads to an advanced sarcopenic phenotype in older mice.
Bhaskaran S, Pollock N, C Macpherson P, Ahn B, Piekarz KM, Staunton CA, Brown JL, Qaisar R, Vasilaki A, Richardson A, McArdle A, Jackson MJ, Brooks SV, Van Remmen H. Bhaskaran S, et al. Among authors: piekarz km. Aging Cell. 2020 Oct;19(10):e13225. doi: 10.1111/acel.13225. Epub 2020 Sep 4. Aging Cell. 2020. PMID: 32886862 Free PMC article.
Cancer cachexia in a mouse model of oxidative stress.
Brown JL, Lawrence MM, Ahn B, Kneis P, Piekarz KM, Qaisar R, Ranjit R, Bian J, Pharaoh G, Brown C, Peelor FF 3rd, Kinter MT, Miller BF, Richardson A, Van Remmen H. Brown JL, et al. Among authors: piekarz km. J Cachexia Sarcopenia Muscle. 2020 Dec;11(6):1688-1704. doi: 10.1002/jcsm.12615. Epub 2020 Sep 12. J Cachexia Sarcopenia Muscle. 2020. PMID: 32918528 Free PMC article.
Scavenging mitochondrial hydrogen peroxide by peroxiredoxin 3 overexpression attenuates contractile dysfunction and muscle atrophy in a murine model of accelerated sarcopenia.
Ahn B, Ranjit R, Kneis P, Xu H, Piekarz KM, Freeman WM, Kinter M, Richardson A, Ran Q, Brooks SV, Van Remmen H. Ahn B, et al. Among authors: piekarz km. Aging Cell. 2022 Mar;21(3):e13569. doi: 10.1111/acel.13569. Epub 2022 Feb 24. Aging Cell. 2022. PMID: 35199907 Free PMC article.
Neuronal deletion of MnSOD in mice leads to demyelination, inflammation and progressive paralysis that mimics phenotypes associated with progressive multiple sclerosis.
Bhaskaran S, Kumar G, Thadathil N, Piekarz KM, Mohammed S, Lopez SD, Qaisar R, Walton D, Brown JL, Murphy A, Smith N, Saunders D, Beckstead MJ, Plafker S, Lewis TL Jr, Towner R, Deepa SS, Richardson A, Axtell RC, Van Remmen H. Bhaskaran S, et al. Among authors: piekarz km. Redox Biol. 2023 Feb;59:102550. doi: 10.1016/j.redox.2022.102550. Epub 2022 Nov 26. Redox Biol. 2023. PMID: 36470129 Free PMC article.
Senolytic treatment does not mitigate oxidative stress-induced muscle atrophy but improves muscle force generation in CuZn superoxide dismutase knockout mice.
Borowik AK, Lawrence MM, Peelor FF 3rd, Piekarz KM, Crosswhite A, Richardson A, Miller BF, Van Remmen H, Brown JL. Borowik AK, et al. Among authors: piekarz km. Geroscience. 2024 Jun;46(3):3219-3233. doi: 10.1007/s11357-024-01070-x. Epub 2024 Jan 18. Geroscience. 2024. PMID: 38233728 Free PMC article.
16 results