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Dynamic modeling of α-synuclein aggregation in dopaminergic neuronal system indicates points of neuroprotective intervention: experimental validation with implications for Parkinson's therapy.
Sultana Z, Paleologou KE, Al-Mansoori KM, Ardah MT, Singh N, Usmani S, Jiao H, Martin FL, Bharath MM, Vali S, El-Agnaf OM. Sultana Z, et al. Among authors: ardah mt. Neuroscience. 2011 Dec 29;199:303-17. doi: 10.1016/j.neuroscience.2011.10.018. Epub 2011 Oct 20. Neuroscience. 2011. PMID: 22056602
α-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer.
Fauvet B, Mbefo MK, Fares MB, Desobry C, Michael S, Ardah MT, Tsika E, Coune P, Prudent M, Lion N, Eliezer D, Moore DJ, Schneider B, Aebischer P, El-Agnaf OM, Masliah E, Lashuel HA. Fauvet B, et al. Among authors: ardah mt. J Biol Chem. 2012 May 4;287(19):15345-64. doi: 10.1074/jbc.M111.318949. Epub 2012 Feb 7. J Biol Chem. 2012. PMID: 22315227 Free PMC article.
Generation and characterization of novel conformation-specific monoclonal antibodies for α-synuclein pathology.
Vaikath NN, Majbour NK, Paleologou KE, Ardah MT, van Dam E, van de Berg WD, Forrest SL, Parkkinen L, Gai WP, Hattori N, Takanashi M, Lee SJ, Mann DM, Imai Y, Halliday GM, Li JY, El-Agnaf OM. Vaikath NN, et al. Among authors: ardah mt. Neurobiol Dis. 2015 Jul;79:81-99. doi: 10.1016/j.nbd.2015.04.009. Epub 2015 Apr 30. Neurobiol Dis. 2015. PMID: 25937088
37 results