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Identification and analyses of inhibitors targeting apolipoprotein(a) kringle domains KIV-7, KIV-10, and KV provide insight into kringle domain function.
Sandmark J, Tigerström A, Akerud T, Althage M, Antonsson T, Blaho S, Bodin C, Boström J, Chen Y, Dahlén A, Eriksson PO, Evertsson E, Fex T, Fjellström O, Gustafsson D, Herslöf M, Hicks R, Jarkvist E, Johansson C, Kalies I, Karlsson Svalstedt B, Kartberg F, Legnehed A, Martinsson S, Moberg A, Ridderström M, Rosengren B, Sabirsh A, Thelin A, Vinblad J, Wellner AU, Xu B, Östlund-Lindqvist AM, Knecht W. Sandmark J, et al. Among authors: eriksson po. J Biol Chem. 2020 Apr 10;295(15):5136-5151. doi: 10.1074/jbc.RA119.011251. Epub 2020 Mar 4. J Biol Chem. 2020. PMID: 32132173 Free PMC article.
Creating novel activated factor XI inhibitors through fragment based lead generation and structure aided drug design.
Fjellström O, Akkaya S, Beisel HG, Eriksson PO, Erixon K, Gustafsson D, Jurva U, Kang D, Karis D, Knecht W, Nerme V, Nilsson I, Olsson T, Redzic A, Roth R, Sandmark J, Tigerström A, Öster L. Fjellström O, et al. Among authors: eriksson po. PLoS One. 2015 Jan 28;10(1):e0113705. doi: 10.1371/journal.pone.0113705. eCollection 2015. PLoS One. 2015. PMID: 25629509 Free PMC article.
Exploring the Active Site of the Antibacterial Target MraY by Modified Tunicamycins.
Hering J, Dunevall E, Snijder A, Eriksson PO, Jackson MA, Hartman TM, Ting R, Chen H, Price NPJ, Brändén G, Ek M. Hering J, et al. Among authors: eriksson po. ACS Chem Biol. 2020 Nov 20;15(11):2885-2895. doi: 10.1021/acschembio.0c00423. Epub 2020 Nov 9. ACS Chem Biol. 2020. PMID: 33164499 Free article.
Dapiglutide, a novel dual GLP-1 and GLP-2 receptor agonist, attenuates intestinal insufficiency in a murine model of short bowel.
Reiner J, Berlin P, Held J, Thiery J, Skarbaliene J, Griffin J, Russell W, Eriksson PO, Berner-Hansen M, Ehlers L, Vollmar B, Jaster R, Witte M, Lamprecht G. Reiner J, et al. Among authors: eriksson po. JPEN J Parenter Enteral Nutr. 2022 Jul;46(5):1107-1118. doi: 10.1002/jpen.2286. Epub 2021 Nov 18. JPEN J Parenter Enteral Nutr. 2022. PMID: 34705281
112 results