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Page 1
Bridge helix arginines play a critical role in Cas9 sensitivity to mismatches.
Bratovič M, Fonfara I, Chylinski K, Gálvez EJC, Sullivan TJ, Boerno S, Timmermann B, Boettcher M, Charpentier E. Bratovič M, et al. Among authors: fonfara i. Nat Chem Biol. 2020 May;16(5):587-595. doi: 10.1038/s41589-020-0490-4. Epub 2020 Mar 2. Nat Chem Biol. 2020. PMID: 32123387
Engineering of temperature- and light-switchable Cas9 variants.
Richter F, Fonfara I, Bouazza B, Schumacher CH, Bratovič M, Charpentier E, Möglich A. Richter F, et al. Among authors: fonfara i. Nucleic Acids Res. 2016 Nov 16;44(20):10003-10014. doi: 10.1093/nar/gkw930. Epub 2016 Oct 15. Nucleic Acids Res. 2016. PMID: 27744350 Free PMC article.
Switchable Cas9.
Richter F, Fonfara I, Gelfert R, Nack J, Charpentier E, Möglich A. Richter F, et al. Among authors: fonfara i. Curr Opin Biotechnol. 2017 Dec;48:119-126. doi: 10.1016/j.copbio.2017.03.025. Epub 2017 Apr 26. Curr Opin Biotechnol. 2017. PMID: 28456061 Review.
Improved bi-allelic modification of a transcriptionally silent locus in patient-derived iPSC by Cas9 nickase.
Eggenschwiler R, Moslem M, Fráguas MS, Galla M, Papp O, Naujock M, Fonfara I, Gensch I, Wähner A, Beh-Pajooh A, Mussolino C, Tauscher M, Steinemann D, Wegner F, Petri S, Schambach A, Charpentier E, Cathomen T, Cantz T. Eggenschwiler R, et al. Among authors: fonfara i. Sci Rep. 2016 Dec 2;6:38198. doi: 10.1038/srep38198. Sci Rep. 2016. PMID: 27910942 Free PMC article.
Identification of conserved features of LAGLIDADG homing endonucleases.
Grishin A, Fonfara I, Alexeevski A, Spirin S, Zanegina O, Karyagina A, Alexeyevsky D, Wende W. Grishin A, et al. Among authors: fonfara i. J Bioinform Comput Biol. 2010 Jun;8(3):453-69. doi: 10.1142/s0219720010004665. J Bioinform Comput Biol. 2010. PMID: 20556856