Vennerstrom JL - Search Results

1

Ligand-based design of GLUT inhibitors as potential antitumor agents.

Almahmoud S, Jin W, Geng L, Wang J, Wang X, Vennerstrom JL, Zhong HA. Almahmoud S, et al. Among authors: vennerstrom jl. Bioorg Med Chem. 2020 Apr 1;28(7):115395. doi: 10.1016/j.bmc.2020.115395. Epub 2020 Feb 18. Bioorg Med Chem. 2020. PMID: 32113844

2

Bisquinolines. 1. N,N-bis(7-chloroquinolin-4-yl)alkanediamines with potential against chloroquine-resistant malaria.

Vennerstrom JL, Ellis WY, Ager AL Jr, Andersen SL, Gerena L, Milhous WK. Vennerstrom JL, et al. J Med Chem. 1992 May 29;35(11):2129-34. doi: 10.1021/jm00089a025. J Med Chem. 1992. PMID: 1597862

3

Bisquinolines. 2. Antimalarial N,N-bis(7-chloroquinolin-4-yl)heteroalkanediamines.

Vennerstrom JL, Ager AL Jr, Dorn A, Andersen SL, Gerena L, Ridley RG, Milhous WK. Vennerstrom JL, et al. J Med Chem. 1998 Oct 22;41(22):4360-4. doi: 10.1021/jm9803828. J Med Chem. 1998. PMID: 9784111

4

Depentylation of [3H-pentyl]methyl-n-amylnitrosamine by rat esophageal and liver microsomes and by rat and human cytochrome P450 isoforms.

Chen SC, Wang X, Xu G, Zhou L, Vennerstrom JL, Gonzalez F, Gelboin HV, Mirvish SS. Chen SC, et al. Among authors: vennerstrom jl. Cancer Res. 1999 Jan 1;59(1):91-8. Cancer Res. 1999. PMID: 9892192

5

Synthesis and antimalarial activity of 11 dispiro-1,2,4,5-tetraoxane analogues of WR 148999. 7,8,15,16-Tetraoxadispiro[5.2.5.2]hexadecanes substituted at the 1 and 10 positions with unsaturated and polar functional groups.

Dong Y, Matile H, Chollet J, Kaminsky R, Wood JK, Vennerstrom JL. Dong Y, et al. Among authors: vennerstrom jl. J Med Chem. 1999 Apr 22;42(8):1477-80. doi: 10.1021/jm980698f. J Med Chem. 1999. PMID: 10212135

6

Structural specificity of chloroquine-hematin binding related to inhibition of hematin polymerization and parasite growth.

Vippagunta SR, Dorn A, Matile H, Bhattacharjee AK, Karle JM, Ellis WY, Ridley RG, Vennerstrom JL. Vippagunta SR, et al. Among authors: vennerstrom jl. J Med Chem. 1999 Nov 4;42(22):4630-9. doi: 10.1021/jm9902180. J Med Chem. 1999. PMID: 10579825

7

Synthesis and antimalarial activity of sixteen dispiro-1,2,4, 5-tetraoxanes: alkyl-substituted 7,8,15,16-tetraoxadispiro[5.2.5. 2]hexadecanes.

Vennerstrom JL, Dong Y, Andersen SL, Ager AL Jr, Fu H, Miller RE, Wesche DL, Kyle DE, Gerena L, Walters SM, Wood JK, Edwards G, Holme AD, McLean WG, Milhous WK. Vennerstrom JL, et al. J Med Chem. 2000 Jul 13;43(14):2753-8. doi: 10.1021/jm0000766. J Med Chem. 2000. PMID: 10893313

8

Carbon isosteres of the 4-aminopyridine substructure of chloroquine: effects on pK(a), hematin binding, inhibition of hemozoin formation, and parasite growth.

Cheruku SR, Maiti S, Dorn A, Scorneaux B, Bhattacharjee AK, Ellis WY, Vennerstrom JL. Cheruku SR, et al. Among authors: vennerstrom jl. J Med Chem. 2003 Jul 3;46(14):3166-9. doi: 10.1021/jm030038x. J Med Chem. 2003. PMID: 12825955

9

Dispiro-1,2,4-trioxane analogues of a prototype dispiro-1,2,4-trioxolane: mechanistic comparators for artemisinin in the context of reaction pathways with iron(II).

Tang Y, Dong Y, Wang X, Sriraghavan K, Wood JK, Vennerstrom JL. Tang Y, et al. Among authors: vennerstrom jl. J Org Chem. 2005 Jun 24;70(13):5103-10. doi: 10.1021/jo050385+. J Org Chem. 2005. PMID: 15960511

10

Spiro and dispiro-1,2,4-trioxolanes as antimalarial peroxides: charting a workable structure-activity relationship using simple prototypes.

Dong Y, Chollet J, Matile H, Charman SA, Chiu FC, Charman WN, Scorneaux B, Urwyler H, Santo Tomas J, Scheurer C, Snyder C, Dorn A, Wang X, Karle JM, Tang Y, Wittlin S, Brun R, Vennerstrom JL. Dong Y, et al. Among authors: vennerstrom jl. J Med Chem. 2005 Jul 28;48(15):4953-61. doi: 10.1021/jm049040u. J Med Chem. 2005. PMID: 16033274

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