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Page 1
Phenotyping Reveals Targets of a Pseudo-Natural-Product Autophagy Inhibitor.
Foley DJ, Zinken S, Corkery D, Laraia L, Pahl A, Wu YW, Waldmann H. Foley DJ, et al. Among authors: zinken s. Angew Chem Int Ed Engl. 2020 Jul 20;59(30):12470-12476. doi: 10.1002/anie.202000364. Epub 2020 Apr 21. Angew Chem Int Ed Engl. 2020. PMID: 32108411 Free PMC article.
Natural product fragment combination to performance-diverse pseudo-natural products.
Grigalunas M, Burhop A, Zinken S, Pahl A, Gally JM, Wild N, Mantel Y, Sievers S, Foley DJ, Scheel R, Strohmann C, Antonchick AP, Waldmann H. Grigalunas M, et al. Among authors: zinken s. Nat Commun. 2021 Mar 25;12(1):1883. doi: 10.1038/s41467-021-22174-4. Nat Commun. 2021. PMID: 33767198 Free PMC article.
Image-Based Morphological Profiling Identifies a Lysosomotropic, Iron-Sequestering Autophagy Inhibitor.
Laraia L, Garivet G, Foley DJ, Kaiser N, Müller S, Zinken S, Pinkert T, Wilke J, Corkery D, Pahl A, Sievers S, Janning P, Arenz C, Wu Y, Rodriguez R, Waldmann H. Laraia L, et al. Among authors: zinken s. Angew Chem Int Ed Engl. 2020 Mar 27;59(14):5721-5729. doi: 10.1002/anie.201913712. Epub 2020 Jan 24. Angew Chem Int Ed Engl. 2020. PMID: 31769920 Free PMC article.
Thermal proteome profiling identifies the membrane-bound purinergic receptor P2X4 as a target of the autophagy inhibitor indophagolin.
Carnero Corrales MA, Zinken S, Konstantinidis G, Rafehi M, Abdelrahman A, Wu YW, Janning P, Müller CE, Laraia L, Waldmann H. Carnero Corrales MA, et al. Among authors: zinken s. Cell Chem Biol. 2021 Dec 16;28(12):1750-1757.e5. doi: 10.1016/j.chembiol.2021.02.017. Epub 2021 Mar 15. Cell Chem Biol. 2021. PMID: 33725479 Free article.
Discovery of Covalent Inhibitors Targeting the Transcriptional Enhanced Associate Domain Central Pocket.
Karatas H, Akbarzadeh M, Adihou H, Hahne G, Pobbati AV, Yihui Ng E, Guéret SM, Sievers S, Pahl A, Metz M, Zinken S, Dötsch L, Nowak C, Thavam S, Friese A, Kang C, Hong W, Waldmann H. Karatas H, et al. Among authors: zinken s. J Med Chem. 2020 Oct 22;63(20):11972-11989. doi: 10.1021/acs.jmedchem.0c01275. Epub 2020 Oct 1. J Med Chem. 2020. PMID: 32907324 Free PMC article.