van Lier JJ - Search Results

1

Absorption, distribution, metabolism, and excretion of cenerimod, a selective S1P₁ receptor modulator in healthy subjects.

Boof ML, van Lier JJ, English S, Fischer H, Ufer M, Dingemanse J. Boof ML, et al. Among authors: van lier jj. Xenobiotica. 2020 Aug;50(8):947-956. doi: 10.1080/00498254.2020.1736688. Epub 2020 Mar 9. Xenobiotica. 2020. PMID: 32105166

2

Absorption, distribution, metabolism and excretion of the P2Y12 receptor antagonist selatogrel after subcutaneous administration in healthy subjects.

Ufer M, Huynh C, van Lier JJ, Caroff E, Fischer H, Dingemanse J. Ufer M, et al. Among authors: van lier jj. Xenobiotica. 2020 Apr;50(4):427-434. doi: 10.1080/00498254.2019.1646440. Epub 2019 Aug 7. Xenobiotica. 2020. PMID: 31322041

3

Absorption, Distribution, Metabolism, and Excretion of [¹⁴C]iptacopan in Healthy Male Volunteers and in In Vivo and In Vitro Studies.

James AD, Kulmatycki K, Poller B, Romeo AA, Van Lier JJ, Klein K, Pearson D. James AD, et al. Among authors: van lier jj. Drug Metab Dispos. 2023 Jul;51(7):873-883. doi: 10.1124/dmd.123.001290. Epub 2023 Jun 12. Drug Metab Dispos. 2023. PMID: 37308298

4

Metabolism and disposition of the αv-integrin ß3/ß5 receptor antagonist cilengitide, a cyclic polypeptide, in humans.

Becker A, von Richter O, Kovar A, Scheible H, van Lier JJ, Johne A. Becker A, et al. Among authors: van lier jj. J Clin Pharmacol. 2015 Jul;55(7):815-24. doi: 10.1002/jcph.482. Epub 2015 Mar 23. J Clin Pharmacol. 2015. PMID: 25683324 Clinical Trial.

5

An evaluation of human ADME and mass balance studies using regular or low doses of radiocarbon.

Roffel AF, van Marle SP, van Lier JJ, Hartstra J, van Hoogdalem EJ. Roffel AF, et al. Among authors: van lier jj. J Labelled Comp Radiopharm. 2016 Dec;59(14):619-626. doi: 10.1002/jlcr.3473. J Labelled Comp Radiopharm. 2016. PMID: 28000265 Review.

6

Open-label, single-center, phase I trial to investigate the mass balance and absolute bioavailability of the highly selective oral MET inhibitor tepotinib in healthy volunteers.

Johne A, Scheible H, Becker A, van Lier JJ, Wolna P, Meyring M. Johne A, et al. Among authors: van lier jj. Invest New Drugs. 2020 Oct;38(5):1507-1519. doi: 10.1007/s10637-020-00926-1. Epub 2020 Mar 27. Invest New Drugs. 2020. PMID: 32221754 Free PMC article. Clinical Trial.

7

Evobrutinib, a covalent Bruton's tyrosine kinase inhibitor: Mass balance, elimination route, and metabolism in healthy participants.

Scheible H, Dyroff M, Seithel-Keuth A, Harrison-Moench E, Mammasse N, Port A, Bachmann A, Dong J, van Lier JJ, Tracewell W, Mitchell D. Scheible H, et al. Among authors: van lier jj. Clin Transl Sci. 2021 Nov;14(6):2420-2430. doi: 10.1111/cts.13108. Epub 2021 Aug 10. Clin Transl Sci. 2021. PMID: 34374206 Free PMC article.

8

Absorption, metabolism and excretion of [(14)C]mirabegron (YM178), a potent and selective β(3)-adrenoceptor agonist, after oral administration to healthy male volunteers.

Takusagawa S, van Lier JJ, Suzuki K, Nagata M, Meijer J, Krauwinkel W, Schaddelee M, Sekiguchi M, Miyashita A, Iwatsubo T, van Gelderen M, Usui T. Takusagawa S, et al. Among authors: van gelderen m, van lier jj. Drug Metab Dispos. 2012 Apr;40(4):815-24. doi: 10.1124/dmd.111.043588. Epub 2012 Jan 23. Drug Metab Dispos. 2012. PMID: 22269146 Clinical Trial.

9

Excretion and metabolism of desogestrel in healthy postmenopausal women.

Verhoeven CH, Gloudemans RH, Peeters PA, van Lier JJ, Verheggen FT, Groothuis GM, Rietjens IM, Vos RM. Verhoeven CH, et al. Among authors: van lier jj. J Steroid Biochem Mol Biol. 2001 Nov;78(5):471-80. doi: 10.1016/s0960-0760(01)00124-8. J Steroid Biochem Mol Biol. 2001. PMID: 11738557

10

Absorption, metabolism and excretion of the GLP-1 analogue semaglutide in humans and nonclinical species.

Jensen L, Helleberg H, Roffel A, van Lier JJ, Bjørnsdottir I, Pedersen PJ, Rowe E, Derving Karsbøl J, Pedersen ML. Jensen L, et al. Among authors: van lier jj. Eur J Pharm Sci. 2017 Jun 15;104:31-41. doi: 10.1016/j.ejps.2017.03.020. Epub 2017 Mar 16. Eur J Pharm Sci. 2017. PMID: 28323117 Free article.

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