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One-Pot Procedure for the Synthesis of Asymmetric Substituted Ureido Benzene Sulfonamides as Effective Inhibitors of Carbonic Anhydrase Enzymes.
Vannozzi G, Vullo D, Angeli A, Ferraroni M, Combs J, Lomelino C, Andring J, Mckenna R, Bartolucci G, Pallecchi M, Lucarini L, Sgambellone S, Masini E, Carta F, Supuran CT. Vannozzi G, et al. J Med Chem. 2022 Jan 13;65(1):824-837. doi: 10.1021/acs.jmedchem.1c01906. Epub 2021 Dec 27. J Med Chem. 2022. PMID: 34958217
The three-tails approach as a new strategy to improve selectivity of action of sulphonamide inhibitors against tumour-associated carbonic anhydrase IX and XII.
Bonardi A, Bua S, Combs J, Lomelino C, Andring J, Osman SM, Toti A, Di Cesare Mannelli L, Gratteri P, Ghelardini C, McKenna R, Nocentini A, Supuran CT. Bonardi A, et al. J Enzyme Inhib Med Chem. 2022 Dec;37(1):930-939. doi: 10.1080/14756366.2022.2053526. J Enzyme Inhib Med Chem. 2022. PMID: 35306936 Free PMC article.
Ibuprofen: a weak inhibitor of carbonic anhydrase II.
Combs J, Andring J, McKenna R. Combs J, et al. Acta Crystallogr F Struct Biol Commun. 2022 Nov 1;78(Pt 11):395-402. doi: 10.1107/S2053230X22009761. Epub 2022 Oct 14. Acta Crystallogr F Struct Biol Commun. 2022. PMID: 36322425 Free PMC article.
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