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Acute cellular and vascular responses to photodynamic therapy using EGFR-targeted nanobody-photosensitizer conjugates studied with intravital optical imaging and magnetic resonance imaging.
de Bruijn HS, Mashayekhi V, Schreurs TJL, van Driel PBAA, Strijkers GJ, van Diest PJ, Lowik CWGM, Seynhaeve ALB, Hagen TLMT, Prompers JJ, Henegouwen PMPVBE, Robinson DJ, Oliveira S. de Bruijn HS, et al. Among authors: van driel pbaa, van diest pj. Theranostics. 2020 Jan 20;10(5):2436-2452. doi: 10.7150/thno.37949. eCollection 2020. Theranostics. 2020. PMID: 32089747 Free PMC article.
Molecular imaging with a fluorescent antibody targeting carbonic anhydrase IX can successfully detect hypoxic ductal carcinoma in situ of the breast.
van Brussel AS, Adams A, Vermeulen JF, Oliveira S, van der Wall E, Mali WP, van Diest PJ, van Bergen En Henegouwen PM. van Brussel AS, et al. Among authors: van der wall e, van bergen en henegouwen pm, van diest pj. Breast Cancer Res Treat. 2013 Jul;140(2):263-72. doi: 10.1007/s10549-013-2635-6. Epub 2013 Jul 17. Breast Cancer Res Treat. 2013. PMID: 23860929
Hypoxia-Targeting Fluorescent Nanobodies for Optical Molecular Imaging of Pre-Invasive Breast Cancer.
van Brussel AS, Adams A, Oliveira S, Dorresteijn B, El Khattabi M, Vermeulen JF, van der Wall E, Mali WP, Derksen PW, van Diest PJ, van Bergen En Henegouwen PM. van Brussel AS, et al. Among authors: van der wall e, van bergen en henegouwen pm, van diest pj. Mol Imaging Biol. 2016 Aug;18(4):535-44. doi: 10.1007/s11307-015-0909-6. Mol Imaging Biol. 2016. PMID: 26589824 Free PMC article.
Optical imaging of pre-invasive breast cancer with a combination of VHHs targeting CAIX and HER2 increases contrast and facilitates tumour characterization.
Kijanka MM, van Brussel AS, van der Wall E, Mali WP, van Diest PJ, van Bergen En Henegouwen PM, Oliveira S. Kijanka MM, et al. Among authors: van brussel as, van der wall e, van bergen en henegouwen pm, van diest pj. EJNMMI Res. 2016 Dec;6(1):14. doi: 10.1186/s13550-016-0166-y. Epub 2016 Feb 10. EJNMMI Res. 2016. PMID: 26860296 Free PMC article.
EGFR targeted nanobody-photosensitizer conjugates for photodynamic therapy in a pre-clinical model of head and neck cancer.
van Driel PBAA, Boonstra MC, Slooter MD, Heukers R, Stammes MA, Snoeks TJA, de Bruijn HS, van Diest PJ, Vahrmeijer AL, van Bergen En Henegouwen PMP, van de Velde CJH, Löwik CWGM, Robinson DJ, Oliveira S. van Driel PBAA, et al. Among authors: van diest pj, van bergen en henegouwen pmp, van de velde cjh. J Control Release. 2016 May 10;229:93-105. doi: 10.1016/j.jconrel.2016.03.014. Epub 2016 Mar 15. J Control Release. 2016. PMID: 26988602 Free PMC article.
Tumor-Specific Uptake of Fluorescent Bevacizumab-IRDye800CW Microdosing in Patients with Primary Breast Cancer: A Phase I Feasibility Study.
Lamberts LE, Koch M, de Jong JS, Adams ALL, Glatz J, Kranendonk MEG, Terwisscha van Scheltinga AGT, Jansen L, de Vries J, Lub-de Hooge MN, Schröder CP, Jorritsma-Smit A, Linssen MD, de Boer E, van der Vegt B, Nagengast WB, Elias SG, Oliveira S, Witkamp AJ, Mali WPTM, Van der Wall E, van Diest PJ, de Vries EGE, Ntziachristos V, van Dam GM. Lamberts LE, et al. Among authors: van der wall e, van diest pj, van dam gm, van der vegt b. Clin Cancer Res. 2017 Jun 1;23(11):2730-2741. doi: 10.1158/1078-0432.CCR-16-0437. Epub 2016 Nov 9. Clin Cancer Res. 2017. PMID: 28119364 Clinical Trial.
Nanobody-targeted photodynamic therapy induces significant tumor regression of trastuzumab-resistant HER2-positive breast cancer, after a single treatment session.
Deken MM, Kijanka MM, Beltrán Hernández I, Slooter MD, de Bruijn HS, van Diest PJ, van Bergen En Henegouwen PMP, Lowik CWGM, Robinson DJ, Vahrmeijer AL, Oliveira S. Deken MM, et al. Among authors: van diest pj, van bergen en henegouwen pmp. J Control Release. 2020 Jul 10;323:269-281. doi: 10.1016/j.jconrel.2020.04.030. Epub 2020 Apr 21. J Control Release. 2020. PMID: 32330574 Free PMC article.
Intraoperative MET-receptor targeted fluorescent imaging and spectroscopy for lymph node detection in papillary thyroid cancer: novel diagnostic tools for more selective central lymph node compartment dissection.
Jonker PKC, Metman MJH, Sondorp LHJ, Sywak MS, Gill AJ, Jansen L, Links TP, van Diest PJ, van Ginhoven TM, Löwik CWGM, Nguyen AH, Coppes RP, Robinson DJ, van Dam GM, van Hemel BM, Fehrmann RSN, Kruijff S. Jonker PKC, et al. Among authors: van ginhoven tm, van hemel bm, van diest pj, van dam gm. Eur J Nucl Med Mol Imaging. 2022 Aug;49(10):3557-3570. doi: 10.1007/s00259-022-05763-3. Epub 2022 Apr 7. Eur J Nucl Med Mol Imaging. 2022. PMID: 35389070 Free PMC article.
834 results