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Multiple inducers and novel roles of autoantibodies against the obligatory NMDAR subunit NR1: a translational study from chronic life stress to brain injury.
Pan H, Steixner-Kumar AA, Seelbach A, Deutsch N, Ronnenberg A, Tapken D, von Ahsen N, Mitjans M, Worthmann H, Trippe R, Klein-Schmidt C, Schopf N, Rentzsch K, Begemann M, Wienands J, Stöcker W, Weissenborn K, Hollmann M, Nave KA, Lühder F, Ehrenreich H. Pan H, et al. Among authors: luhder f. Mol Psychiatry. 2021 Jun;26(6):2471-2482. doi: 10.1038/s41380-020-0672-1. Epub 2020 Feb 24. Mol Psychiatry. 2021. PMID: 32089545 Free PMC article.
Neuropsychiatric disease relevance of circulating anti-NMDA receptor autoantibodies depends on blood-brain barrier integrity.
Hammer C, Stepniak B, Schneider A, Papiol S, Tantra M, Begemann M, Sirén AL, Pardo LA, Sperling S, Mohd Jofrry S, Gurvich A, Jensen N, Ostmeier K, Lühder F, Probst C, Martens H, Gillis M, Saher G, Assogna F, Spalletta G, Stöcker W, Schulz TF, Nave KA, Ehrenreich H. Hammer C, et al. Among authors: luhder f. Mol Psychiatry. 2014 Oct;19(10):1143-9. doi: 10.1038/mp.2013.110. Epub 2013 Sep 3. Mol Psychiatry. 2014. PMID: 23999527
Uncoupling the widespread occurrence of anti-NMDAR1 autoantibodies from neuropsychiatric disease in a novel autoimmune model.
Pan H, Oliveira B, Saher G, Dere E, Tapken D, Mitjans M, Seidel J, Wesolowski J, Wakhloo D, Klein-Schmidt C, Ronnenberg A, Schwabe K, Trippe R, Mätz-Rensing K, Berghoff S, Al-Krinawe Y, Martens H, Begemann M, Stöcker W, Kaup FJ, Mischke R, Boretius S, Nave KA, Krauss JK, Hollmann M, Lühder F, Ehrenreich H. Pan H, et al. Among authors: luhder f. Mol Psychiatry. 2019 Oct;24(10):1489-1501. doi: 10.1038/s41380-017-0011-3. Epub 2018 Feb 9. Mol Psychiatry. 2019. PMID: 29426955 Free PMC article.
Inducing sterile pyramidal neuronal death in mice to model distinct aspects of gray matter encephalitis.
Wilke JBH, Hindermann M, Moussavi A, Butt UJ, Dadarwal R, Berghoff SA, Sarcheshmeh AK, Ronnenberg A, Zihsler S, Arinrad S, Hardeland R, Seidel J, Lühder F, Nave KA, Boretius S, Ehrenreich H. Wilke JBH, et al. Among authors: luhder f. Acta Neuropathol Commun. 2021 Jul 2;9(1):121. doi: 10.1186/s40478-021-01214-6. Acta Neuropathol Commun. 2021. PMID: 34215338 Free PMC article.
Autoantibodies against NMDA receptor 1 modify rather than cause encephalitis.
Wilke JBH, Hindermann M, Berghoff SA, Zihsler S, Arinrad S, Ronnenberg A, Barnkothe N, Steixner-Kumar AA, Röglin S, Stöcker W, Hollmann M, Nave KA, Lühder F, Ehrenreich H. Wilke JBH, et al. Among authors: luhder f. Mol Psychiatry. 2021 Dec;26(12):7746-7759. doi: 10.1038/s41380-021-01238-3. Epub 2021 Jul 30. Mol Psychiatry. 2021. PMID: 34331009 Free PMC article.
NMDAR1 autoantibodies amplify behavioral phenotypes of genetic white matter inflammation: a mild encephalitis model with neuropsychiatric relevance.
Arinrad S, Wilke JBH, Seelbach A, Doeren J, Hindermann M, Butt UJ, Steixner-Kumar AA, Spieth L, Ronnenberg A, Pan H, Berghoff SA, Hollmann M, Lühder F, Nave KA, Bechter K, Ehrenreich H. Arinrad S, et al. Among authors: luhder f. Mol Psychiatry. 2022 Dec;27(12):4974-4983. doi: 10.1038/s41380-021-01392-8. Epub 2021 Dec 6. Mol Psychiatry. 2022. PMID: 34866134 Free PMC article.
T cell development critically depends on prethymic stromal patched expression.
Uhmann A, van den Brandt J, Dittmann K, Hess I, Dressel R, Binder C, Lühder F, Christiansen H, Fassnacht M, Bhandoola A, Wienands J, Reichardt HM, Hahn H. Uhmann A, et al. Among authors: luhder f. J Immunol. 2011 Mar 15;186(6):3383-91. doi: 10.4049/jimmunol.1001939. Epub 2011 Feb 11. J Immunol. 2011. PMID: 21317383
Tyrphostin AG126 exerts neuroprotection in CNS inflammation by a dual mechanism.
Menzfeld C, John M, van Rossum D, Regen T, Scheffel J, Janova H, Götz A, Ribes S, Nau R, Borisch A, Boutin P, Neumann K, Bremes V, Wienands J, Reichardt HM, Lühder F, Tischner D, Waetzig V, Herdegen T, Teismann P, Greig I, Müller M, Pukrop T, Mildner A, Kettenmann H, Brück W, Prinz M, Rotshenker S, Weber MS, Hanisch UK. Menzfeld C, et al. Among authors: luhder f. Glia. 2015 Jun;63(6):1083-99. doi: 10.1002/glia.22803. Epub 2015 Mar 2. Glia. 2015. PMID: 25731696
99 results