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Multiple inducers and novel roles of autoantibodies against the obligatory NMDAR subunit NR1: a translational study from chronic life stress to brain injury.
Mol Psychiatry. 2021 Jun;26(6):2471-2482. doi: 10.1038/s41380-020-0672-1. Epub 2020 Feb 24.
Mol Psychiatry. 2021.
PMID: 32089545
Free PMC article.
All naturally occurring autoantibodies against the NMDA receptor subunit NR1 have pathogenic potential irrespective of epitope and immunoglobulin class.
Castillo-Gómez E, Oliveira B, Tapken D, Bertrand S, Klein-Schmidt C, Pan H, Zafeiriou P, Steiner J, Jurek B, Trippe R, Prüss H, Zimmermann WH, Bertrand D, Ehrenreich H, Hollmann M.
Castillo-Gómez E, et al. Among authors: klein schmidt c.
Mol Psychiatry. 2017 Dec;22(12):1776-1784. doi: 10.1038/mp.2016.125. Epub 2016 Aug 9.
Mol Psychiatry. 2017.
PMID: 27502473
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Uncoupling the widespread occurrence of anti-NMDAR1 autoantibodies from neuropsychiatric disease in a novel autoimmune model.
Pan H, Oliveira B, Saher G, Dere E, Tapken D, Mitjans M, Seidel J, Wesolowski J, Wakhloo D, Klein-Schmidt C, Ronnenberg A, Schwabe K, Trippe R, Mätz-Rensing K, Berghoff S, Al-Krinawe Y, Martens H, Begemann M, Stöcker W, Kaup FJ, Mischke R, Boretius S, Nave KA, Krauss JK, Hollmann M, Lühder F, Ehrenreich H.
Pan H, et al. Among authors: klein schmidt c.
Mol Psychiatry. 2019 Oct;24(10):1489-1501. doi: 10.1038/s41380-017-0011-3. Epub 2018 Feb 9.
Mol Psychiatry. 2019.
PMID: 29426955
Free PMC article.
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Discovery of triazole-bridged aryl adamantane analogs as an intriguing class of multifunctional agents for treatment of Alzheimer's disease.
Gutti G, Leifeld J, Kakarla R, Bajad NG, Ganeshpurkar A, Kumar A, Krishnamurthy S, Klein-Schmidt C, Tapken D, Hollmann M, Singh SK.
Gutti G, et al. Among authors: klein schmidt c.
Eur J Med Chem. 2023 Nov 5;259:115670. doi: 10.1016/j.ejmech.2023.115670. Epub 2023 Jul 24.
Eur J Med Chem. 2023.
PMID: 37515920
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